Utilization patterns of antidepressants between 1991 and 2011 in a population-based cohort of middle-aged and elderly - 23/07/14
, L.E. Visser b, g, 4Bienvenido a EM-consulte, la referencia de los profesionales de la salud.
El acceso al texto completo de este artículo requiere una suscripción.
| páginas | 6 |
| Iconografías | 3 |
| Vídeos | 0 |
| Otros | 0 |
Abstract |
Background |
In middle-aged and older patients in whom antidepressant use increased in last decades, patterns of use might be of concern The objective of this study was to investigate the patterns of prevalence, incidence and duration of antidepressant use in an ageing population.
Methods |
All participants (aged>45 years) from the population-based Rotterdam Study were followed from January 1st 1991 until death, loss to follow-up, or end of the study period (December 31st 2011). Antidepressant drug dispensing, based on pharmacy records, were subdivided into Tricyclic Antidepressants (TCAs), Selective Serotonin Reuptake Inhibitors (SSRIs) and other antidepressants. One-year prevalence, 5-year incidence and duration of antidepressant use were calculated.
Results |
Yearly prevalence of antidepressant use increased from 3.9% in 1991 to 8.3% of the population in 2011. The increase in SSRI use was 5.8-fold, whereas use of other antidepressants doubled and TCA use remained stable over time. Incidence of all antidepressants decreased from 23.9 to 14.2 per 1000 person-years between 1992 and 2011. The duration of a first treatment episode increased over time.
Conclusion |
Despite the prevalence of antidepressant use increased over time, incidence did not, which is most likely explained by a longer treatment duration and recurrent episodes.
El texto completo de este artículo está disponible en PDF.Keywords : Antidepressant agents, Drug utilization, Middle-aged and elderly
Esquema
Vol 29 - N° 6
P. 365-370 - août 2014 Regresar al número
Artículo precedente
- Poor longitudinal continuity of care is associated with an increased mortality rate among patients with mental disorders: Results from the French National Health Insurance Reimbursement Database
- N. Hoertel, F. Limosin, H. Leleu
- Short-term functional outcome and premorbid adjustment in clinical high-risk patients. Results of the EPOS project
- R.K.R. Salokangas, M. Heinimaa, T. From, E. Löyttyniemi, T. Ilonen, S. Luutonen, J. Hietala, T. Svirskis, H.G. von Reventlow, G. Juckel, D. Linszen, P. Dingemans, M. Birchwood, P. Patterson, F. Schultze-Lutter, S. Ruhrmann, J. Klosterkötter, EPOS group
Bienvenido a EM-consulte, la referencia de los profesionales de la salud.
El acceso al texto completo de este artículo requiere una suscripción.
Bienvenido a EM-consulte, la referencia de los profesionales de la salud.
La compra de artículos no está disponible en este momento.
¿Ya suscrito a @@106933@@ revista ?