This article reviews the management of degenerative lumbosacral stenosis. Degenerative lumbosacral stenosis occurs when soft tissue and bony changes, possibly in conjunction with abnormal motion of the lumbosacral joint, impinge on the nerve roots or vasculature of the cauda equina. It occurs most frequently in middle-aged dogs of medium to large breed, especially the German Shepherd dog. Common signs are lumbosacral pain, lameness, pelvic limb weakness and ataxia, and urinary incontinence. Diagnosis is based on clinical features and imaging studies. Decompressive surgery is effective in most patients.