Índice

• • ·Editorial Board

    Artículo :116817

    

• Review Articles

  • ·The multifaceted mechanisms of Dihydrotanshinone I in the treatment of tumors

    Artículo :116635

    Jing Yue, Dingqian Hao, Yingzheng Wang, Jinhao Guo, Shengyang Liu, Linghui Meng, Jianliang Liu

    Resumen Resumen Esquema Esquema  
  • ·miR-192 family in breast cancer: Regulatory mechanisms and diagnostic value

    Artículo :116620

    Mingxuan Yu, Hua Du, Caihong Zhang, Yingxu Shi

    Resumen Resumen Esquema Esquema  
  • ·Engineering the protein corona: Strategies, effects, and future directions in nanoparticle therapeutics

    Artículo :116627

    Tianyu Zhao, Mingli Ren, Jiajie Shi, Haijiao Wang, Jing Bai, Wenli Du, Bai Xiang

    Resumen Resumen Esquema Esquema  
  • ·New insights into the roles of Irisin in diabetic cardiomyopathy and vascular diseases

    Artículo :116631

    Tiandong Zhang, Qian Yi, Wenhua Huang, Jianguo Feng, Huan Liu

    Resumen Resumen Esquema Esquema  
  • ·Targeting the crosstalk between estrogen receptors and membrane growth factor receptors in breast cancer treatment: Advances and opportunities

    Artículo :116615

    Shunchao Yan, Jiale Ji, Zhijie Zhang, Murshid Imam, Hong Chen, Duo Zhang, Jinpeng Wang

    Resumen Resumen Esquema Esquema  
  • ·EZH2: The roles in targeted therapy and mechanisms of resistance in breast cancer

    Artículo :116624

    Yun Chen, Hongyan Zhu, Yi Luo, Shuangmei Tong, Yan Liu

    Resumen Resumen Esquema Esquema   
  • ·Therapeutic potential: The role of mesenchymal stem cells from diverse sources and their derived exosomes in diabetic nephropathy

    Artículo :116672

    Lixin Liu, Yiman Chen, Xuan Li, Juan Wang, Lina Yang

    Resumen Resumen Esquema Esquema  
  • ·Diagnostic and therapeutic value of human serpin family proteins

    Artículo :116618

    Sabina Janciauskiene, Urszula Lechowicz, Magdalena Pelc, Beata Olejnicka, Joanna Chorostowska-Wynimko

    Resumen Resumen Esquema Esquema  
  • ·Effects of chronic stress on cancer development and the therapeutic prospects of adrenergic signaling regulation

    Artículo :116609

    Hao Zhang, Yuwei Yang, Yan Cao, Jingzhi Guan

    Resumen Resumen Esquema Esquema  
  • ·Cardiovascular outcomes and molecular targets for the cardiac effects of Sodium-Glucose Cotransporter 2 Inhibitors: A systematic review

    Artículo :116650

    Rosalinda Madonna, Filippo Biondi, Mattia Alberti, Sandra Ghelardoni, Letizia Mattii, Alberto D’Alleva

    Resumen Resumen Esquema Esquema   
  • ·Mitochondrial dynamics dysfunction: Unraveling the hidden link to depression

    Artículo :116656

    Haiyang Chen, Mei Lu, Qin Lyu, Liuqing Shi, Chuntong Zhou, Mingjie Li, Shiyu Feng, Xicai Liang, Xin Zhou, Lu Ren

    Resumen Resumen Esquema Esquema  
  • ·H2AX: A key player in DNA damage response and a promising target for cancer therapy

    Artículo :116663

    Kirti S. Prabhu, Shilpa Kuttikrishnan, Nuha Ahmad, Ummu Habeeba, Zahwa Mariyam, Muhammad Suleman, Ajaz A. Bhat, Shahab Uddin

    Resumen Resumen Esquema Esquema  
  • ·Current status of superoxide dismutase 2 on oral disease progression by supervision of ROS

    Artículo :116605

    Dian Ding, Na Li, Yihong Ge, Hongle Wu, Jinzhao Yu, Wei Qiu, Fuchun Fang

    Resumen Resumen Esquema Esquema  
  • ·The roles of epigenetic regulation in graft-versus-host disease

    Artículo :116652

    Yimin Wang, Qi Liu, Lei Deng, Xiting Ma, Yuling Gong, Yifei Wang, Fang Zhou

    Resumen Resumen Esquema Esquema  
  • ·Role of antioxidants in the neurobiology of drug addiction: An update

    Artículo :116604

    Piotr Kamiński, Małgorzata Lorek, Jędrzej Baszyński, Tadeusz Tadrowski, Edward Jacek Gorzelańczyk, Julia Feit, Halina Tkaczenko, Jakub Owoc, Alina Woźniak, Natalia Kurhaluk

    Resumen Resumen Esquema Esquema  
  • ·Voltage-gated potassium channel 1.3: A promising molecular target in multiple disease therapy

    Artículo :116651

    Sixuan Cheng, Dawei Jiang, Xiaoli Lan, Kun Liu, Cheng Fan

    Resumen Resumen Esquema Esquema  
  • ·Unveiling the promise of PD1/PD-L1: A new dawn in immunotherapy for cholangiocarcinoma

    Artículo :116659

    Fei Chen, Jian Sheng, Xiaoping Li, Zhaofeng Gao, Siqi Zhao, Lingyu Hu, Minjie Chen, Jianguo Fei, Zhengwei Song

    Resumen Resumen Esquema Esquema  
  • ·Early signs of neurodegenerative diseases: Possible mechanisms and targets for Golgi stress

    Artículo :116646

    Mengyu Liu, Ying Duan, Jianru Dong, Kaisong Zhang, Xin Jin, Menglin Gao, Huachao Jia, Ju Chen, Mingyan Liu, Minjie Wei, Xin Zhong

    Resumen Resumen Esquema Esquema  
  • ·CaMKII activity and metabolic imbalance-related neurological diseases: Focus on vascular dysfunction, synaptic plasticity, amyloid beta accumulation, and lipid metabolism

    Artículo :116688

    Jeongsik Yong, Juhyun Song

    Resumen Resumen Esquema Esquema  
  • ·The crosstalk between glucose metabolism and telomerase regulation in cancer

    Artículo :116643

    Mingrui Huang, Mingdi Liu, Ruijia Wang, Yifan Man, Honglan Zhou, Zhi-Xiang Xu, Yishu Wang

    Resumen Resumen Esquema Esquema  
  • ·Effects of opioid drugs on immune function in cancer patients

    Artículo :116665

    Yunqi Li, Lina Sun, Qinglian Zhou, An Jie Lee, Lingyan Wang, Rui Zhang, Shoushi Wang

    Resumen Resumen Esquema Esquema  
  • ·A Current Understanding of FXR in NAFLD: The multifaceted regulatory role of FXR and novel lead discovery for drug development

    Artículo :116658

    Yuhong Tang, Yujuan Fan, Yiming Wang, Dong Wang, Qingyu Huang, Tongqing Chen, Xinyue Cao, Cailing Wen, Xiaoyan Shen, Jian Li, Yan You

    Resumen Resumen Esquema Esquema  
  • ·Natural products as the therapeutic strategies for addiction

    Artículo :116687

    Rui Yu, De-Lei Kong, Cai Liao, Ya-Jie Yu, Zhen-Wei He, Yun Wang

    Resumen Resumen Esquema Esquema  
  • ·NLRP3 inflammasome and its role in autoimmune diseases: A promising therapeutic target

    Artículo :116679

    Wenxuan Ren, Ying Sun, Lei Zhao, Xiaoguang Shi

    Resumen Resumen Esquema Esquema  
  • ·The Blood Virome: A new frontier in biomedical science

    Artículo :116608

    Abraham J. Kandathil, David L. Thomas

    Resumen Resumen Esquema Esquema   
  • ·Targeting regulated cell death (RCD) in hematological malignancies: Recent advances and therapeutic potential

    Artículo :116667

    Yu Zhang, Xiangxiang Zhou

    Resumen Resumen Esquema Esquema  
  • ·Targeted delivery of anti-osteoporosis therapy: Bisphosphonate-modified nanosystems and composites

    Artículo :116699

    Shaoyan Shi, Honghao Duan, Xuehai Ou

    Resumen Resumen Esquema Esquema  
  • ·Exploring the multifaceted role of GCN1: Implications in cellular responses and disease pathogenesis

    Artículo :116681

    Xinying Zheng, Jinze Shen, Hongting Jiang, Mei Tian, Qurui Wang, Kailin Guo, Ruixiu Chen, Qing Xia, Qibin Yan, Lihua Du, Shiwei Duan

    Resumen Resumen Esquema Esquema  
  • ·Wnt/β-catenin signalling, epithelial-mesenchymal transition and crosslink signalling in colorectal cancer cells

    Artículo :116685

    Luanbiao Sun, Jianpeng Xing, Xuanpeng Zhou, Xinyuan Song, Shuohui Gao

    Resumen Resumen Esquema Esquema  
  • ·Advanced nanoparticle strategies for optimizing RNA therapeutic delivery in neurodegenerative disorders

    Artículo :116691

    Narges Naimi, Homa Seyedmirzaei, Zahra Hassannejad, Alireza Soltani Khaboushan

    Resumen Resumen Esquema Esquema  
  • ·Relationship between the cGAS−STING and NF-κB pathways-role in neurotoxicity

    Artículo :116698

    Shiyin Zhong, Qiongli Zhou, Jirui Yang, Zhimin Zhang, Xin Zhang, Jingjing Liu, Xuhong Chang, Hui Wang

    Resumen Resumen Esquema Esquema  
  • ·The interplay between mitochondrial dysfunction and NLRP3 inflammasome in multiple sclerosis: Therapeutic implications and animal model studies

    Artículo :116673

    Alireza Shadab, Mohammad Abbasi-Kolli, Mansoore Saharkhiz, Seyed Hamed Ahadi, Behrooz Shokouhi, Javid Sadri Nahand

    Resumen Resumen Esquema Esquema  
  • ·YAP in development and disease: Navigating the regulatory landscape from retina to brain

    Artículo :116703

    Yaqin Zhao, Bin Sun, Xuefei Fu, Zhuan Zuo, Huan Qin, Kai Yao

    Resumen Resumen Esquema Esquema  
  • ·Kaempferol efficacy in metabolic diseases: Molecular mechanisms of action in diabetes mellitus, obesity, non-alcoholic fatty liver disease, steatohepatitis, and atherosclerosis

    Artículo :116694

    Yu-xin Yao, Yu-jie Yu, Shu Dai, Chao-yang Zhang, Xin-yan Xue, Meng-ling Zhou, Chen-hao Yao, Yun-xia Li

    Resumen Resumen Esquema Esquema  
  • ·The role and future prospects of artificial intelligence algorithms in peptide drug development

    Artículo :116709

    Zhiheng Chen, Ruoxi Wang, Junqi Guo, Xiaogang Wang

    Resumen Resumen Esquema Esquema  
  • ·The role of mitochondrial damage-associated molecular patterns in acute pancreatitis

    Artículo :116690

    Yan Zhou, Xiaoyi Huang, Yinglu Jin, Minhao Qiu, Peter C. Ambe, Zarrin Basharat, Wandong Hong

    Resumen Resumen Esquema Esquema  
  • ·Natural products as glycolytic inhibitors for cervical cancer treatment: A comprehensive review

    Artículo :116708

    Qun Liu, Xiuhan Chen, Yurong Tan, Jiao Liu, Mingya Zhu, Delin Li, Yijie Zhou, Tiane Zhang, Qiao zhi Yin

    Resumen Resumen Esquema Esquema  
  • ·Targeted delivery strategies: The interactions and applications of nanoparticles in liver diseases

    Artículo :116702

    Xiandi Meng, Ge Zhu, Yong-Guang Yang, Tianmeng Sun

    Resumen Resumen Esquema Esquema  
  • ·Ferroptosis in ulcerative colitis: Potential mechanisms and promising therapeutic targets

    Artículo :116722

    Dan Long, Chenhan Mao, Yingtao Huang, Yin Xu, Ying Zhu

    Resumen Resumen Esquema Esquema  
  • ·Advances of Schwann cells in peripheral nerve regeneration: From mechanism to cell therapy

    Artículo :116645

    Chuqiao Wei, Yuanxin Guo, Zhen Ci, Mucong Li, Yidi Zhang, Yanmin Zhou

    Resumen Resumen Esquema Esquema  
  • ·Novel insight into the role of A-kinase anchoring proteins (AKAPs) in ischemic stroke and therapeutic potentials

    Artículo :116715

    Ziyu He, Letian Xie, Jiyong Liu, Xuan Wei, Wenli Zhang, Zhigang Mei

    Resumen Resumen Esquema Esquema  
  • ·Association of histone modification with the development of schizophrenia

    Artículo :116747

    Yun-zhou Chen, Xiu-mei Zhu, Peng Lv, Xi-kai Hou, Ying Pan, Ang Li, Zhe Du, Jin-feng Xuan, Xiaochong Guo, Jia-xin Xing, Kun Liu, Jun Yao

    Resumen Resumen Esquema Esquema  
  • ·GPR41 and GPR43: From development to metabolic regulation

    Artículo :116735

    Do-Hyung Lee, Min-Tae Kim, Joo-Hui Han

    Resumen Resumen Esquema Esquema  
  • ·Short-chain fatty acids: Important components of the gut-brain axis against AD

    Artículo :116601

    Yan Huang, Yi Feng Wang, Jing Miao, Rui Fang Zheng, Jin Yao Li

    Resumen Resumen Esquema Esquema  
  • ·RNA epigenetics in pulmonary diseases: Insights into methylation modification of lncRNAs in lung cancer

    Artículo :116704

    Junjie Jiang, Minghao Duan, Zheng Wang, Yuwei Lai, Chunfang Zhang, Chaojun Duan

    Resumen Resumen Esquema Esquema  
  • ·Beyond monotherapy: An era ushering in combinations of PARP inhibitors with immune checkpoint inhibitors for solid tumors

    Artículo :116733

    Lin Zhou, Yicong Wan, Lin Zhang, Huangyang Meng, Lin Yuan, Shulin Zhou, Wenjun Cheng, Yi Jiang

    Resumen Resumen Esquema Esquema  
  • ·Role of pattern recognition receptors in the development of MASLD and potential therapeutic applications

    Artículo :116724

    Lili Yu, Feifei Gao, Yaoxin Li, Dan Su, Liping Han, Yueming Li, Xuehan Zhang, Zhiwei Feng

    Resumen Resumen Esquema Esquema  
  • ·E3 ligases and DUBs target ferroptosis: A potential therapeutic strategy for neurodegenerative diseases

    Artículo :116753

    Linxia Lu, Cili Jifu, Jun Xia, Jingtao Wang

    Resumen Resumen Esquema Esquema  
  • ·Propolis as an autophagy modulator in relation to its roles in redox balance and inflammation regulation

    Artículo :116745

    R. Lesmana, S. Tandean, A. Christoper, A.A. Suwantika, N. Wathoni, R. Abdulah, J. Fearnley, V. Bankova, F. Zulhendri

    Resumen Resumen Esquema Esquema  
  • ·Exploring new mechanisms of Imeglimin in diabetes treatment: Amelioration of mitochondrial dysfunction

    Artículo :116755

    Yilin Li, Nenngjun Lou, Xiaojing Liu, Xianghua Zhuang, Shihong Chen

    Resumen Resumen Esquema Esquema  
  • ·Exploring immune-related pathogenesis in lung injury: Providing new insights Into ALI/ARDS

    Artículo :116773

    Jiajing Zheng, Ying Li, Xianbin Kong, Jinhe Guo

    Resumen Resumen Esquema Esquema  
  • ·Targeting autophagy in diabetic cardiomyopathy: From molecular mechanisms to pharmacotherapy

    Artículo :116790

    Jie Li, Yingying Xie, Shuwen Zheng, Haoming He, Zhe Wang, Xuexi Li, Siqi Jiao, Dong Liu, Furong Yang, Hailing Zhao, Ping Li, Yihong Sun

    Resumen Resumen Esquema Esquema  
  • ·Targeting apoptosis in clear cell renal cell carcinoma

    Artículo :116805

    Adam Kowalewski, Jędrzej Borowczak, Mateusz Maniewski, Karol Gostomczyk, Dariusz Grzanka, Łukasz Szylberg

    Resumen Resumen Esquema Esquema  
  • ·Newsights of endoplasmic reticulum in hypoxia

    Artículo :116812

    Lu Guan, Rili Ge, Shuang Ma

    Resumen Resumen Esquema Esquema  
  • ·An unmet need for pharmacology: Treatments for radiation-induced gastrointestinal mucositis

    Artículo :116767

    Yan Zhou, Kun Li, David L. Adelson

    Resumen Resumen Esquema Esquema  
  • ·A peripheral system disease—Pulmonary hypertension

    Artículo :116787

    Yang Sun, Chen Chen, Qian Yan, Siying Wang, Yong Tan, Junpeng Long, Yuting Lin, Shuangcheng Ning, Jin Wang, Shusheng Zhang, Qidi Ai, Shasha Liu

    Resumen Resumen Esquema Esquema  

• Original Articles

  • ·Pharmacological inhibition of the Src homology phosphatase 2 confers partial protection in a mouse model of alcohol-associated liver disease

    Artículo :116590

    Ming-Fo Hsu, Shinichiro Koike, Chang-Shan Chen, Sonia M. Najjar, Tzu-Ching Meng, Fawaz G. Haj

    Resumen Resumen Esquema Esquema   
  • ·Lapatinib combined with doxorubicin causes dose-dependent cardiotoxicity partially through activating the p38MAPK signaling pathway in zebrafish embryos

    Artículo :116637

    Ke Du, Yuting Liu, Lu Zhang, Lixia Peng, Wenjing Dong, Yajie Jiang, Mingming Niu, Yuanchao Sun, Chuanhong Wu, Yujuan Niu, Yonghe Ding

    Resumen Resumen Esquema Esquema  
  • ·Protective role of hydrogen sulfide against diabetic cardiomyopathy by inhibiting pyroptosis and myocardial fibrosis

    Artículo :116613

    Maojun Liu, Cheng Zeng, Yifeng Zhang, Ying Xin, Simin Deng, Xinqun Hu

    Resumen Resumen Esquema Esquema   
  • ·The effects of Atractylodes macrocephala extract BZEP self-microemulsion based on gut–liver axis HDL/LPS signaling pathway to ameliorate metabolic dysfunction-associated fatty liver disease in rats

    Artículo :116519

    Bo Li, Xiao-Feng Jiang, Ying-Jie Dong, Yi-Piao Zhang, Xing-Li-Shang He, Cheng-Liang Zhou, Yan-Yan Ding, Ning Wang, Yi-Bin Wang, Wan-Qi Cheng, Ning-Hua Jiang, Jie Su, Gui-Yuan Lv, Su-Hong Chen

    Resumen Resumen Esquema Esquema  
  • ·Sex-specific pharmacokinetic response to phytoestrogens in Drosophila melanogaster

    Artículo :116612

    Nadiia Sadova, Bernhard Blank-Landeshammer, David Curic, Marcus Iken, Julian Weghuber

    Resumen Resumen Esquema Esquema   
  • ·The antiglycation potential of H1 receptor antagonists – in vitro studies in bovine serum albumin model and in silico molecular docking analyses

    Artículo :116632

    Grzegorz Biedrzycki, Blanka Wolszczak – Biedrzycka, Justyna Dorf, Daniel Michalak, Małgorzata Żendzian – Piotrowska, Anna Zalewska, Mateusz Maciejczyk

    Resumen Resumen Esquema Esquema  
  • ·Helminth-derived molecules improve 5-fluorouracil treatment on experimental colon tumorigenesis

    Artículo :116628

    Mónica G. Mendoza-Rodríguez, Daniela Medina-Reyes, Cuauhtémoc A. Sánchez-Barrera, Karen V. Fernández-Muñoz, Verónica García-Castillo, Jorge L. Ledesma-Torres, Marisol I. González-González, José L. Reyes, Carlos Pérez-Plascencia, Miriam Rodríguez-Sosa, Felipe Vaca-Paniagua, Marco A. Meraz, Luis I. Terrazas

    Resumen Resumen Esquema Esquema   
  • ·Designing multitarget ligands for neurodegenerative diseases with improved permeability trough PLGA nanoencapsulation

    Artículo :116626

    Vanesa Nozal, Paula Fernández-Gómez, Alfonso García-Rubia, Loreto Martínez-González, Eva P. Cuevas, Eva Carro, Valle Palomo, Ana Martínez

    Resumen Resumen Esquema Esquema   
  • ·Pseudolaric acid B suppresses NSCLC progression through the ROS/AMPK/mTOR/autophagy signalling pathway

    Artículo :116614

    Dan Luo, Fang He, Jingyun Liu, Xueting Dong, Mengying Fang, Yuling Liang, Mengqin Chen, Xuemei Gui, Wenjun Wang, Li Zeng, Xianming Fan, Qibiao Wu

    Resumen Resumen Esquema Esquema  
  • ·Senolytics ameliorate the failure of bone regeneration through the cell senescence-related inflammatory signalling pathway

    Artículo :116606

    Xinchen Wang, Yue Zhou, Chuyi Luo, Jianxin Zhao, Yuna Ji, Zheng Wang, Pengchao Zheng, Dingji Li, Yuhan Shi, Aki Nishiura, Naoyuki Matsumoto, Yoshitomo Honda, Baoshan Xu, Fang Huang

    Resumen Resumen Esquema Esquema   
  • ·PEA-OXA restores cognitive impairments associated with vitamin D deficiency-dependent alterations of the gut microbiota

    Artículo :116600

    Francesca Guida, Monica Iannotta, Michela Perrone, Rosmara Infantino, Giada Giorgini, Antimo Fusco, Ida Marabese, Iolanda Manzo, Carmela Belardo, Emanuele Di Martino, Salvatore Pagano, Serena Boccella, Cristoforo Silvestri, Livio Luongo, Vincenzo Di Marzo, Sabatino Maione

    Resumen Resumen Esquema Esquema   
  • ·YL-109 attenuates sepsis-associated multiple organ injury through inhibiting the ERK/AP-1 axis and pyroptosis by upregulating CHIP

    Artículo :116633

    Miao Wang, Jia Liao, Wan Lin, Lucen Jiang, Kangli Peng, Xingyu Su, Hang Li, Huadong Wang, Yiyang Wang

    Resumen Resumen Esquema Esquema   
  • ·Restoring bone-fat equilibrium: Baicalin's impact on P38 MAPK pathway for treating diabetic osteoporosis

    Artículo :116571

    Weicheng Qin, Qi Shang, Gengyang Shen, Bing Li, Peng Zhang, Yuzhuo Zhang, Wenhua Zhao, Honglin Chen, Huiwen Liu, Bin Xie, Zhida Zhang, Hui Ren, Xiaobing Jiang

    Resumen Resumen Esquema Esquema   
  • ·Polysaccharides from Dendrobium officinale delay diabetic kidney disease interstitial fibrosis through LncRNA XIST/TGF-β1

    Artículo :116636

    Yongqiang Zhang, Yiyao Deng, Yuqi Yang, Zhi Yang, Yangyang Yin, Jia Xie, Jie Ding, Yu Shang, Yan Zha, Jing Yuan

    Resumen Resumen Esquema Esquema   
  • ·Therapeutic potentials of Hibiscus trionum: Antioxidant, anti-lipid peroxidative, hypoglycemic, and hepatoprotective effects in type 1 diabetic rats

    Artículo :116630

    Sedef Ziyanok-Demirtas

    Resumen Resumen Esquema Esquema  
  • ·Preclinical imaging evaluation of a bispecific antibody targeting hPD1/CTLA4 using humanized mice

    Artículo :116669

    Xingguo Hou, Song Liu, Ziqing Zeng, Zilei Wang, Jin Ding, Yan Chen, Xiangyu Gao, Jianghua Wang, Guanxi Xiao, Baiyong Li, Hua Zhu, Zhi Yang

    Resumen Resumen Esquema Esquema   
  • ·Hypotensive drugs mitigate the high-sodium diet-induced pro-inflammatory activation of mouse macrophages in vivo

    Artículo :116648

    Martyna Cieślik, Spencer D. Strobel, Paweł Bryniarski, Hanna Twardowska, Adam Chmielowski, Michał Rudek, Dominik Felkle, Katarzyna Zięba, Konrad Kaleta, Mateusz Jarczyński, Bernadeta Nowak, Krzysztof Bryniarski, Katarzyna Nazimek

    Resumen Resumen Esquema Esquema   
  • ·NETs induce ferroptosis of endothelial cells in LPS-ALI through SDC-1/HS and downstream pathways

    Artículo :116621

    Yuxin Fei, Xiao Huang, Fangyu Ning, Tiantian Qian, Jinfeng Cui, Xiaozhi Wang, Xiao Huang

    Resumen Resumen Esquema Esquema  
  • ·The e-liquid flavoring cinnamaldehyde induces cellular stress responses in human proximal tubule (HK-2) kidney cells

    Artículo :116666

    Ashley Cox, Kathleen C. Brown, Christopher Bender, Monica A. Valentovic

    Resumen Resumen Esquema Esquema   
  • ·A novel dosing approach for rituximab in glomerular diseases based on a population pharmacokinetic analysis

    Artículo :116655

    Jan Miroslav Hartinger, Martin Šíma, Zdenka Hrušková, Alena Pilková, Vojtěch Krátký, Romana Ryšavá, Eva Jančová, Daniel Bobek, Jiří Douša, Ivana Francová, Vladimír Tesař, Ondřej Slanař

    Resumen Resumen Esquema Esquema   
  • ·L-DOPA ameliorates hippocampus-based mitochondria respiratory dysfunction caused by GCI/R injury

    Artículo :116664

    Wenzhu Wang, Jingyu Zhao, Zihan Li, Xiaoyu Kang, Ting Li, Nickolay K. Isaev, Elena A. Smirnova, Hui Shen, Lixu Liu, Yan Yu

    Resumen Resumen Esquema Esquema  
  • ·Biological effects and mechanism of β-amyloid aggregation inhibition by penetrable recombinant human HspB5-ACD structural domain protein

    Artículo :116661

    Chang Liu, Xuying Ding, Meijun Zhao, Chen Chen, Xiaojun Zhang, Risheng Zhao, Yutong Chen, Yining Xie

    Resumen Resumen Esquema Esquema  
  • ·DIREN mitigates DSS-induced colitis in mice and attenuates collagen deposition via inhibiting the Wnt/β-catenin and focal adhesion pathways

    Artículo :116671

    Weizhi Lai, Yingying Wang, Chen Huang, Hao Xu, Xunjie Zheng, Ke Li, Jue Wang, Zhaohuan Lou

    Resumen Resumen Esquema Esquema  
  • ·Seedless black Vitis vinifera polyphenols suppress hepatocellular carcinoma in vitro and in vivo by targeting apoptosis, cancer stem cells, and proliferation

    Artículo :116638

    Nadia Z. Shaban, Walaa A. Hegazy, Marwa M. Abu-Serie, Iman M. Talaat, Olfat M. Awad, Noha H. Habashy

    Resumen Resumen Esquema Esquema  
  • ·Mechanistic study of Huangqi Guizhi Wuwu decoction amelioration of doxorubicin-induced cardiotoxicity by reducing oxidative stress and inhibiting cellular pyroptosis

    Artículo :116653

    Yu Chen, Meng Xu, Xiao-Mei Liu, Jian-Xin Wang, Meng-Fan Sun, Ji-Xian Song, Peng Guan, En-Sheng Ji, Na Wang

    Resumen Resumen Esquema Esquema  
  • ·In vitro study of cold atmospheric plasma-activated liquids inhibits malignant melanoma by affecting macrophage polarization through the ROS/JAK2/STAT1 pathway

    Artículo :116657

    Cheng Chen, Shiyun Zhou, Xingyu Yang, Miaomiao Ren, Yongshuang Qi, Yiwen Mao, Chunjun Yang

    Resumen Resumen Esquema Esquema  
  • ·The effects of acteoside on locomotor recovery after spinal cord injury – The role of autophagy and apoptosis signaling pathway

    Artículo :116607

    Shanglong Ning, Yang Chen, Jia Shao, Hui Zhu, Zepei Zhang, Jun Miao

    Resumen Resumen Esquema Esquema  
  • ·Ziprasidone triggers inflammasome signaling via PI3K-Akt-mTOR pathway to promote atrial fibrillation

    Artículo :116649

    Ming-Kun Lu, Yen-Nien Huo, Buh-Yuan Tai, Chih-Yuan Lin, Hsiang-Yu Yang, Chien-Sung Tsai

    Resumen Resumen Esquema Esquema  
  • ·Interplay of OATP1A/1B/2B1 uptake transporters and ABCB1 and ABCG2 efflux transporters in the handling of bilirubin and drugs

    Artículo :116644

    Wenlong Li, Rolf W. Sparidans, Yaogeng Wang, Margarida L.F. Martins, Dirk R. de Waart, Olaf van Tellingen, Ji-Ying Song, Maria C. Lebre, Stéphanie van Hoppe, Els Wagenaar, Jos H. Beijnen, Alfred H. Schinkel

    Resumen Resumen Esquema Esquema   
  • ·Formyl peptide enhances cancer immunotherapy by activating antitumoral neutrophils, and T cells

    Artículo :116670

    Haixia Sun, Shuxin Li, Qiaoli Wang, Chunxiang Luo, Lanyi Zhong, Guohui Wan, Ziqian Li, Gexin Zhao, Xianzhang Bu, Musheng Zeng, Guokai Feng

    Resumen Resumen Esquema Esquema   
  • ·Advancing oral health: Harnessing the potential of chitosan and polyphenols in innovative mouthwash formulation

    Artículo :116654

    Małgorzata Maj, Bartosz Tylkowski, Piotr Konopka, Marta Woźniak-Budych, Katarzyna Staszak, Maciej Staszak, Łukasz Kaźmierski, Anna Bajek, Renata Jastrzab

    Resumen Resumen Esquema Esquema  
  • ·DHEA-S, Androstenedione, 17-β-estradiol signature as novel biomarkers for early prediction of risk of malignant pleural mesothelioma linked to asbestos-exposure: A preliminary investigation

    Artículo :116662

    Barbara Nuvoli, Andrea Sacconi, Grazia Bottillo, Francesca Sciarra, Roberta Libener, Antonio Maconi, Mariantonia Carosi, Giorgio Piperno, Eliuccia Mastropasqua, Maria Papale, Emanuela Camera, Rossella Galati

    Resumen Resumen Esquema Esquema   
  • ·Radiosensitizing effects of heparinized magnetic iron oxide nanoparticles in colon cancer

    Artículo :116668

    Maria V. Shestovskaya, Anna L. Luss, Olga A. Bezborodova, Pavel P. Kulikov, Daria A. Antufrieva, Ekaterina A. Plotnikova, Valentin V. Makarov, Vladimir S. Yudin, Andrey A. Pankratov, Anton A. Keskinov

    Resumen Resumen Esquema Esquema   
  • ·Sevoflurane postconditioning ameliorates cerebral hypoxia/reoxygenation injury in zebrafish involving the Akt/GSK-3β pathway activation and the microtubule-associated protein 2 promotion

    Artículo :116693

    Li Zhang, Mengsi Yang, Zongyi Wang, Dinggang Fan, Fang Shen, Xuezhu Zou, Xiaoyuan Zhang, Su Hu, Bing Hu, Xianwen Hu

    Resumen Resumen Esquema Esquema   
  • ·Combined in vivo effect of N-acylethanolamine-hydrolyzing acid amidase and glycogen synthase kinase-3β inhibition to treat multiple sclerosis

    Artículo :116677

    Stefania Sgroi, Elisa Romeo, Ennio Albanesi, Federica Piccardi, Federico Catalano, Doriana Debellis, Fabio Bertozzi, Angelo Reggiani

    Resumen Resumen Esquema Esquema   
  • ·A comparative study on the protective effects of cuminaldehyde, thymoquinone, and gallic acid against carbon tetrachloride-induced pulmonary and renal toxicity in rats by affecting ROS and NF-κB signaling

    Artículo :116692

    Nadia Z. Shaban, Lamiaa A. El Swify, Marwa M. Abu-Serie, Adham M. Maher, Noha H. Habashy

    Resumen Resumen Esquema Esquema  
  • ·Exploring in vivo combinatorial chemo-immunotherapy: Addressing p97 suppression and immune reinvigoration in pancreatic cancer with tumor microenvironment-responsive nanoformulation

    Artículo :116660

    Yu-Li Lo, Ching-Yao Li, Tsui-Fen Chou, Ching-Ping Yang, Li-Ling Wu, Chun-Jung Chen, Yih-Hsin Chang

    Resumen Resumen Esquema Esquema   
  • ·Alleviation of hepatic insulin resistance and steatosis with NMN via improving endoplasmic reticulum–Mitochondria miscommunication in the liver of HFD mice

    Artículo :116682

    Yumeng Li, Xutong Tian, Qian Yu, Tongtong Bao, Chao Dai, Liang Jiang, Kaimin Niu, Jianying Yang, Shujin Wang, Xin Wu

    Resumen Resumen Esquema Esquema   
  • ·Nicotinamide riboside attenuates myocardial ischemia-reperfusion injury via regulating SIRT3/SOD2 signaling pathway

    Artículo :116689

    Kai Zhao, Jie Tang, Hong Xie, Lin Liu, Qin Qin, Bo Sun, Zheng-hong Qin, Rui Sheng, Jiang Zhu

    Resumen Resumen Esquema Esquema  
  • ·Gonadal efficacy of Thymus quinquecostatus Celakovski: Regulation of testosterone levels in aging mouse models

    Artículo :116700

    Hyun-Yong Kim, Hyuck Se Kwon, Je-Oh Lim, Hyun-Jun Jang, Subramanian Muthamil, Ung Cheol Shin, Ji-Hyo Lyu, Yeo Jin Park, Hyeon-Hwa Nam, Na-young Lee, Hyun-Jeong Oh, Soon-Il Yun, Jong-Sik Jin, Jun Hong Park

    Resumen Resumen Esquema Esquema  
  • ·Multiple drug-delivery strategies to enhance the pharmacological and toxicological properties of Mefenamic acid

    Artículo :116647

    Claudia Cristiano, Robert J. Cavanagh, Valentina Cuzzucoli Crucitti, Cara Moloney, Eleni Axioti, Emily Dixon, Philippa L. Jacob, Marica Erminia Schiano, Mariarosaria Cuozzo, Fabrizio Maria Liguori, Barbara Rolando, Roberto Russo, Vincenzo Taresco, Federica Sodano, Maria Grazia Rimoli

    Resumen Resumen Esquema Esquema   
  • ·Angelica sinensis polysaccharide combined with cisplatin reverses cisplatin resistance of ovarian cancer by inducing ferroptosis via regulating GPX4

    Artículo :116680

    Weikang Guo, Wanyue Wang, Fei Lei, Ruxin Zheng, Xinyao Zhao, Yuze Gu, Mengdi Yang, Yunshun Tong, Yaoxian Wang

    Resumen Resumen Esquema Esquema   
  • ·MPoMA protects against lung epithelial cell injury via p65 degradation

    Artículo :116674

    Soheun Lee, Suh Jin Yoon, Ji Hyun Oh, Jae-Sang Ryu, Yunjeong Park, Eun Sook Hwang

    Resumen Resumen Esquema Esquema   
  • ·Inhibition of activin receptor 2 signalling ameliorates metabolic dysfunction–associated steatotic liver disease in western diet/L-NAME induced cardiometabolic disease

    Artículo :116683

    Julia Swan, Zoltán Szabó, Juliana Peters, Outi Kummu, Anna Kemppi, Lea Rahtu-Korpela, Anja Konzack, Jukka Hakkola, Arja Pasternack, Olli Ritvos, Risto Kerkelä, Johanna Magga

    Resumen Resumen Esquema Esquema   
  • ·Suppression of PERK/eIF2α/CHOP pathway enhances oridonin-induced apoptosis by inhibiting autophagy in Small-Cell lung cancer cells

    Artículo :116684

    Linhao Xu, Yuxin Jiang, Yanli Bi, Senwen Zheng, Yirong Wu, Yihao Wu, Yizhou Xu, Jian Chen

    Resumen Resumen Esquema Esquema   
  • ·Kokusaginine attenuates renal fibrosis by inhibiting the PI3K/AKT signaling pathway

    Artículo :116695

    Yuxin Wang, Yuanyuan Han, Kaiqi Shang, Jing Xiao, Lijian Tao, Zhangzhe Peng, Shao Liu, Yueping Jiang

    Resumen Resumen Esquema Esquema   
  • ·Sulforaphane decreases oxidative stress and inhibits NLRP3 inflammasome activation in a mouse model of ulcerative colitis

    Artículo :116706

    Zi-juan Zhou, Jian-yi Dong, Yang Qiu, Guo-lin Zhang, Kun Wei, Li-heng He, Yi-ning Sun, Hao-zheng Jiang, Shuang-shuang Zhang, Xin-rui Guo, Jing-yu Wang, Da-peng Chen

    Resumen Resumen Esquema Esquema  
  • ·The discovery of a novel pyrrolo[2,3-b]pyridine as a selective CDK8 inhibitor offers a new approach against psoriasis

    Artículo :116705

    Yao Yao Yan, Yu Meng Wang, Jun Hao Shen, Yu Jie Jian, Cen Cen Lei, Quan Wang, Chao Liu, Xing Xing Zhang, Xin Hua Liu

    Resumen Resumen Esquema Esquema   
  • ·PDE5 inhibition mitigates heart failure in hyperlipidemia

    Artículo :116710

    Wuqing Huang, Xi Yang, Naiqi Zhang, Keyuan Chen, Jun Xiao, Zhihuang Qiu, Sujun You, Ziting Gao, Jianguang Ji, Liangwan Chen

    Resumen Resumen Esquema Esquema   
  • ·Cannabinoid levels description in a cohort of patients with chronic and neuropathic pain treated with Cannabis decoction: A possible role of TDM

    Artículo :116686

    Alessandra Manca, Cristina Valz, Francesco Chiara, Jacopo Mula, Alice Palermiti, Martina Billi, Miriam Antonucci, Amedeo De Nicolò, Nicola Luxardo, Daniele Imperiale, Flavio Vischia, David De Cori, Jessica Cusato, Antonio D’Avolio

    Resumen Resumen Esquema Esquema  
  • ·Pharmacogenetics of tenofovir drug transporters in the context of HBV: Is there an impact?

    Artículo :116678

    J. Cusato, A. Manca, A. Palermiti, J. Mula, M. Antonucci, F. Chiara, A. De Nicolò, Tommaso Lupia, Giacomo Stroffolini, L. Boglione, A. D'Avolio

    Resumen Resumen Esquema Esquema  
  • ·Probing Alzheimer's pathology: Exploring the next generation of FDDNP analogues for amyloid β detection

    Artículo :116616

    Luka Rejc, Damijan Knez, Gabriela Molina-Aguirre, Alba Espargaró, Jerneja Kladnik, Anže Meden, Lana Blinc, Matic Lozinšek, Ross D. Jansen-van Vuuren, Matic Rogan, Bruno Aleksander Martek, Jernej Mlakar, Ana Dremelj, Andrej Petrič, Stanislav Gobec, Raimon Sabaté, Mara Bresjanac, Balazs Pinter, Janez Košmrlj

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  • ·Erlotinib suppresses tumorigenesis in a mouse model of colitis-associated cancer

    Artículo :116580

    Max Liu, Xiaoying S. Zhong, Srikruthi S. Krishnachaitanya, Rongliwen Ou, Roderick H. Dashwood, Don W. Powell, Qingjie Li

    Resumen Resumen Esquema Esquema   
  • ·The interaction of plant flavones with amphotericin B: Consequences for its pore-forming ability

    Artículo :116723

    Anna I. Malykhina, Svetlana S. Efimova, Vladimir S. Andriianov, Olga S. Ostroumova

    Resumen Resumen Esquema Esquema   
  • ·Integrated transcriptome and metabolome study reveal the therapeutic effects of nicotinamide riboside and nicotinamide mononucleotide on nonalcoholic fatty liver disease

    Artículo :116701

    Jingting Zhang, Fu Chen

    Resumen Resumen Esquema Esquema   
  • ·Elesclomol-copper synergizes with imidazole ketone erastin by promoting cuproptosis and ferroptosis in myelodysplastic syndromes

    Artículo :116727

    Yan Gao, Feifan Jin, Ping Zhang, Cuiping Zheng, Xiaoyan Zheng, Jing Xie, Ying Lu, Xiangmin Tong, Jing Du, Junyu Zhang, Ying Wang

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  • ·Nocebo expectations rather than placebo expectations affect topical pain relief: A randomized clinical trial

    Artículo :116728

    Mingxiao Yang, Qing S. Li, Raymond E. Baser, Xiaotong Li, Jason Hou, Jun J. Mao

    Resumen Resumen Esquema Esquema  
  • ·CYP3A4 and CYP2C19 genetic polymorphisms and myricetin interaction on tofacitinib metabolism

    Artículo :116421

    Zhize Ye, Hailun Xia, Jinyu Hu, Ya-nan Liu, Anzhou Wang, Jian-ping Cai, Guo-xin Hu, Ren-ai Xu

    Resumen Resumen Esquema Esquema  
  • ·Targeting BTLA with the peptide inhibitor HVEM(14-39) – A new way to restore the activity of T cells in melanoma

    Artículo :116675

    Karolina Wojciechowicz, Katarzyna Kuncewicz, Jacek Rutkowski, Jacek Jassem, Sylwia Rodziewicz-Motowidło, Anna Wardowska, Marta Spodzieja

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  • ·ABCB1 attenuates brain exposure to the KRAS^G12C inhibitor opnurasib whereas binding to mouse carboxylesterase 1c influences its plasma exposure

    Artículo :116720

    Jamie Rijmers, Irene A. Retmana, Viët Bui, Davinia Arguedas, Maria C. Lebre, Rolf W. Sparidans, Jos H. Beijnen, Alfred H. Schinkel

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  • ·NADPH and NAC synergistically inhibits chronic ocular hypertension-induced neurodegeneration and neuroinflammation through regulating p38/MAPK pathway and peroxidation

    Artículo :116711

    Naiji Yu, Xingdi Wu, Chengshou Zhang, Qiyu Qin, Yuxiang Gu, Weishaer Ke, Xin Liu, Qi Zhang, Zhenjie Liu, Min Chen, Kaijun Wang

    Resumen Resumen Esquema Esquema   
  • ·Cisplatin-activated and hemoglobin-mediated injectable hydrogel system for antitumor chemodynamic and chemotherapy

    Artículo :116713

    Hsun-Tzu Tsen, Tzu-Chieh Sun, To-Kai Lai, Wei-Yuan Huang, Huan-Chih Wang, Tsai-Te Lu, Tzu-Wei Wang

    Resumen Resumen Esquema Esquema   
  • ·Tannic acid inhibits Escherichia coli biofilm formation and underlying molecular mechanisms: Biofilm regulator CsgD

    Artículo :116716

    Jinying Long, Can Yang, JingJing Liu, Chengjun Ma, Min Jiao, Huiming Hu, Jing Xiong, Yang Zhang, Wei Wei, Hongzao Yang, Yuzhang He, Maixun Zhu, Yuandi Yu, Lizhi Fu, Hongwei Chen

    Resumen Resumen Esquema Esquema   
  • ·Hippocampal transcriptomic analyses reveal the potential antiapoptotic mechanism of a novel anticonvulsant agent Q808 on pentylenetetrazol-induced epilepsy in rats

    Artículo :116746

    Xiang Li, Ning Liu, Di Wu, Shu chang Li, Qing Wang, Dian-wen Zhang, Lian-lian Song, Min Huang, Xia Chen, Wei Li

    Resumen Resumen Esquema Esquema   
  • ·12-O-deacetyl-phomoxanthone A inhibits ovarian tumor growth and metastasis by downregulating PDK4

    Artículo :116736

    Chunxia Yang, Shangping Xing, Xia Wei, Junfei Lu, Genshi Zhao, Xiaolin Ma, Ziteng Dai, Xia Liang, Wei Huang, Yanying Liu, Xia Jiang, Dan Zhu

    Resumen Resumen Esquema Esquema   
  • ·Therapeutic antibody engineering for efficient targeted degradation of membrane proteins in lysosomes

    Artículo :116707

    Corentin Gauthier, Morgane Daurat, Lamiaa Mohamed Ahmed Ali, Khaled El Cheikh, Iris El Bahlagui, Camille Taliercio, Elodie Morère, Magali Gary-Bobo, Alain Morère, Marcel Garcia, Marie Maynadier, Ilaria Basile

    Resumen Resumen Esquema Esquema   
  • ·Targeting SAT1 prevents osteoporosis through promoting osteoclast apoptosis

    Artículo :116732

    Zhichun Jin, Hao Xu, Xueyu Sun, Bin Yan, Lin Wang

    Resumen Resumen Esquema Esquema   
  • ·Bispecific T cell engager-armed T cells targeting integrin ανβ6 exhibit enhanced T cell redirection and antitumor activity in cholangiocarcinoma

    Artículo :116718

    Kwanpirom Suwanchiwasiri, Nattaporn Phanthaphol, Chalermchai Somboonpatarakun, Pornpimon Yuti, Jatuporn Sujjitjoon, Piriya Luangwattananun, John Maher, Pa‑thai Yenchitsomanus, Mutita Junking

    Resumen Resumen Esquema Esquema   
  • ·Low-dose cadmium induces lymphangiogenesis through activation of the STAT3 signaling pathway

    Artículo :116741

    Yan Xing, Xia Wang, Jing Liu, Yuanqing Zhang, Huai Tianran, Liang Dong, Jinghui Tian, Ju Liu

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  • ·Galunisertib downregulates mutant type I collagen expression and promotes MSCs osteogenesis in pediatric osteogenesis imperfecta

    Artículo :116725

    Arantza Infante, Natividad Alcorta-Sevillano, Iratxe Macías, Leire Cabodevilla, Dalia Medhat, Brittany Lafaver, Tara K. Crawford, Charlotte L. Phillips, Ana M. Bueno, Belén Sagastizabal, Maitane Arroyo, Ainara Campino, Daniela Gerovska, Marcos Araúzo-Bravo, Blanca Gener, Clara I. Rodríguez

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  • ·Efficient systemic CNS delivery of a therapeutic antisense oligonucleotide with a blood-brain barrier-penetrating ApoE-derived peptide

    Artículo :116737

    Yuan Qi Yeoh, Azin Amin, Brittany Cuic, Doris Tomas, Bradley J. Turner, Fazel Shabanpoor

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  • ·Development and functional evaluation of a hyaluronic acid coated nano-formulation with kaempferol as a novel intra-articular agent for Knee Osteoarthritis treatment

    Artículo :116717

    Ching-Yu Lee, Yu-Chu Chang, Kai-Chiang Yang, Yung-fang Lin, Alexander T.H. Wu, Ching-Li Tseng

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  • ·Development of alginate and alginate sulfate/polycaprolactone nanoparticles for growth factor delivery in wound healing therapy

    Artículo :116750

    Mia Karam, Marwa Faraj, Miran A. Jaffa, Joseph Jelwan, Kawthar Sharaf Aldeen, Nadine Hassan, Rami Mhanna, Ayad A. Jaffa

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  • ·The AMPK activator ATX-304 alters cellular metabolism to protect against cisplatin-induced acute kidney injury

    Artículo :116730

    Marina Katerelos, Kurt Gleich, Geoff Harley, Kim Loh, Jonathan S. Oakhill, Bruce E. Kemp, David P. de Souza, Vinod K. Narayana, Melinda T. Coughlan, Adrienne Laskowski, Naomi X.Y. Ling, Lisa Murray-Segal, Robert Brink, Mardiana Lee, David A. Power, Peter F. Mount

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  • ·Differential gene expression in B cells and T helper cells following high-dose glucocorticoid therapy for multiple sclerosis relapse

    Artículo :116721

    Michael Hecker, Brit Fitzner, Dirk Koczan, Juliane Klehmet, Matthias Grothe, Matthias Schwab, Alexander Winkelmann, Stefanie Meister, Ales Dudesek, Isis Ludwig-Portugall, Klaus Eulitz, Uwe Klaus Zettl

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  • ·Biogenic selenium nanoparticles alleviate intestinal barrier injury in mice through TBC1D15/Fis1/Rab7 pathway

    Artículo :116740

    Xina Dou, Lei Qiao, Xiaofan Song, Jiajing Chang, Xiaonan Zeng, Lixu Zhu, Tianjing Deng, Ge Yang, Chunlan Xu

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  • ·Evaluation of BH3 mimetics as a combination therapy with irradiation in head and neck squamous cell carcinoma

    Artículo :116719

    Katja Korelin, Mayke Oostveen, Wafa Wahbi, Filipp Ianevski, Bruno Cavalcante, Laura Turunen, Ilya Belevich, Ahmed Al-Samadi, Tuula Salo

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  • ·Alpha-tocopherol inhibits ferroptosis and promotes neural function recovery in rats with spinal cord injury via downregulating Alox15

    Artículo :116734

    Rui Zhu, Yu Kang, Qiangwei Li, Kai Peng, Xuanming Shi, Zongsheng Yin, Yong Xuan

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  • ·Distinct neural activities of the cortical layer 2/3 across isoflurane anesthesia: A large-scale simultaneous observation of neurons

    Artículo :116751

    Zilin Wang, Kunsha Chen, Xiaodong Wu, Pengchang Zheng, Ao Li, Yongxin Guo, Xingzheng Gu, Guihua Xiao, Hao Xie, ChaoWei Zhuang, Jiangbei Cao

    Resumen Resumen Esquema Esquema   
  • ·Preclinical development of humanized monoclonal antibodies against CD169 as a broad antiviral therapeutic strategy

    Artículo :116726

    Patricia Resa-Infante, Itziar Erkizia, Xabier Muñiz-Trabudua, Federica Linty, Arthur E.H. Bentlage, Daniel Perez-Zsolt, Jordana Muñoz-Basagoiti, Dàlia Raïch-Regué, Nuria Izquierdo-Useros, Theo Rispens, Gestur Vidarsson, Javier Martinez-Picado

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  • ·Preclinical evaluation of combined therapy with amiodarone and low-dose benznidazole in a mouse model of chronic Trypanosoma cruzi infection

    Artículo :116742

    Juliana Magalhães Chaves Barbosa, Yasmin Pedra-Rezende, Hílton Antônio Mata-Santos, Glaucia Vilar-Pereira, Tatiana Galvão de Melo, Isalira Peroba Ramos, Daniel Gibaldi, Otacilio C. Moreira, Daniela Ferreira Nunes, Marcos Meuser Batista, Joseli Lannes-Vieira, Anissa Daliry, Kelly Salomão

    Resumen Resumen Esquema Esquema   
  • ·Ketamine administration causes cognitive impairment by destroying the circulation function of the glymphatic system

    Artículo :116739

    Xue Wu, Gehua Wen, Lei Yan, Yexin Wang, Xinghua Ren, Guiji Li, Yu Luo, Junbo Shang, Lei Lu, Anca Hermenean, Jun Yao, Baoman Li, Yan Lu, Xu Wu

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  • ·Matrine induces autophagic cell death by triggering ROS/AMPK/mTOR axis and apoptosis in multiple myeloma

    Artículo :116738

    Xue Li, Jifan Zhou, Yixin Ling, Yicheng Tan, Jialing Zhang, Xiaofang Wang, Fanfan Li, Songfu Jiang, Shenghui Zhang, Kang Yu, Yixiang Han

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  • ·Nanocarrier mediated entinostat and oxaliplatin combination therapy displayed enhanced efficacy against pancreatic cancer

    Artículo :116743

    Paras Mani Giri, Ashish Kumar, Philip Salu, Venkatachalem Sathish, Katie Reindl, Sanku Mallik, Buddhadev Layek

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  • ·Vitamin K2 ameliorates osteoarthritis by suppressing ferroptosis and extracellular matrix degradation through activation GPX4’s dual functions

    Artículo :116697

    Qi He, Yuewei Lin, Baihao Chen, Chuyi Chen, Jiaxu Zeng, Xiangyun Dou, Dongling Cai, Chi Zhou, Haibin Wang

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  • ·Gut microbiota mediates the protective effects of β-hydroxybutyrate against cisplatin-induced acute kidney injury

    Artículo :116752

    Ruixue Tian, Xingru Wang, Shuqin Tang, Limei Zhao, Yajie Hao, Rongshan Li, Xiaoshuang Zhou

    Resumen Resumen Esquema Esquema   
  • ·A multifunctional antibody fusion protein 57103 targeting CD24, IL-4R, and α_vβ₃ for treating cancer and regulating the tumor microenvironment

    Artículo :116714

    Xiaowei Xu, Jian Li, Sarra Setrerrahmane, Juan Zhang, Suoqin Shi, Yahui Hu, Dong Lin, Hanmei Xu

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  • ·Omega-3 fatty acid diglyceride emulsions as a novel injectable acute therapeutic in neonatal hypoxic-ischemic brain injury

    Artículo :116749

    Hylde Zirpoli, Maria Eugenia Bernis, Hemmen Sabir, Denny Joseph Manual Kollareth, James A. Hamilton, Nasi Huang, Jesse Ng, Sergey A. Sosunov, Ben Gaebler, Vadim S. Ten, Richard J. Deckelbaum

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  • ·Metabolic profiling reveals the nutraceutical effect of Gongolaria abies-marina and Rosmarinus officinalis extracts in a type 1 diabetes animal model

    Artículo :116731

    Joanna Godzien, Kacper Jablonowski, Francisco J. Ruperez, Adam Kretowski, Michal Ciborowski, Bartlomiej Kalaska

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  • ·Nature-inspired substituted 3-(imidazol-2-yl) morpholines targeting human topoisomerase IIα: Dynophore-derived discovery

    Artículo :116676

    Barbara Herlah, Matej Janežič, Iza Ogris, Simona Golič Grdadolnik, Katja Kološa, Sonja Žabkar, Bojana Žegura, Andrej Perdih

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  • ·Alleviating depressive-like behavior in DSS-induced colitis mice: Exploring naringin and poncirin from Poncirus trifoliata extracts

    Artículo :116770

    Kang-In Lee, Min-Soo Kim, Heung Joo Yuk, Yousang Jo, Hye Jin Kim, Jieun Kim, Hyungjun Kim, Ju-Young Shin, Donghwan Kim, Ki-Sun Park

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  • ·Penicilazaphilone C alleviates allergic airway inflammation and improves the immune microenvironment by hindering the NLRP3 inflammasome

    Artículo :116788

    Yongshu Fu, Feng-Ying Huang, Shu-Zhen Dai, Lin Wang, Xiangdong Zhou, Zhen-You Zheng, Cai-Chun Wang, Guang-Hong Tan, Qi Li

    Resumen Resumen Esquema Esquema   
  • ·A novel LAG3 neutralizing antibody improves cancer immunotherapy by dual inhibition of MHC-II and FGL1 ligand binding

    Artículo :116782

    Dianbao Zuo, Yuankui Zhu, Ke Wang, Youjia Qin, Yiyi Su, Sina Lan, Yunyi Li, Shuang Dong, Yinming Liang, Mingqian Feng

    Resumen Resumen Esquema Esquema   
  • ·Ginsenoside Rb1 mitigates acute catecholamine surge-induced myocardial injuries in part by suppressing STING-mediated macrophage activation

    Artículo :116794

    Yujue Wang, Xinmiao Tang, Jingang Cui, Peiwei Wang, Qinbo Yang, Yu Chen, Teng Zhang

    Resumen Resumen Esquema Esquema   
  • ·Notoginsenoside R1 treatment facilitated Nrf2 nuclear translocation to suppress ferroptosis via Keap1/Nrf2 signaling pathway to alleviated high-altitude myocardial injury

    Artículo :116793

    Yilan Wang, Yongjun Yin, Ying Liu, Caixia Pei, Zherui Shen, Sijing Zhao, Nan Jia, Demei Huang, Xiaomin Wang, Yongcan Wu, Shihua Shi, Yacong He, Zhenxing Wang

    Resumen Resumen Esquema Esquema  
  • ·Cardioprotective potentials of myricetin on doxorubicin-induced cardiotoxicity based on biochemical and transcriptomic analysis

    Artículo :116748

    Jaili Li, Ting Luo, Yao Zhao, Dou Wang, Yuanxiang Jin, Zufang Wu, Guiling Yang, Xingjiang Qi

    Resumen Resumen Esquema Esquema   
  • ·Lactobacillus Plantarum intake mitigates neuropathic pain behavior via enhancing macrophage M2 polarization in a rat model of peripheral neuropathy

    Artículo :116769

    Chun-Ta Huang, Li-Kai Wang, June-Horng Lue, Seu-Hwa Chen, Yi-Ju Tsai

    Resumen Resumen Esquema Esquema  
  • ·Environmental enrichment and the combined interventions of EE and metformin enhance hippocampal neuron survival and hippocampal-dependent memory in type 2 diabetic rats under stress through the BDNF-TrkB signaling pathways

    Artículo :116729

    Teh Rasyidah Ismail, Christina Gertrude Yap, Rakesh Naidu, Lugganya Shri, Narendra Pamidi

    Resumen Resumen Esquema Esquema  
  • ·Ameliorative effect of Nyctanthes arbor-tristis L. by suppression of pentylenetetrazole-induced kindling in mice: An insight from EEG, neurobehavioral and in-silico studies

    Artículo :116791

    Usman Javaid, Syeda Afroz, Waseem Ashraf, Khaled Ahmed Saghir, Faleh Alqahtani, Syed Muhammad Muneeb Anjum, Tanveer Ahmad, Imran Imran

    Resumen Resumen Esquema Esquema  
  • ·Oligopeptide-strategy of targeting at adipose tissue macrophages using ATS-9R/siCcl2 complex for ameliorating insulin resistance in GDM

    Artículo :116775

    Min Wang, Xuyang Chen, Yanshan Shang, Bingnan Chen, Hao Chen, Linwei Zhou, Hongli Li, Dan Zhang, Bailong Tao, Xiaobo Zhou, Hua Zhang

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  • ·Apolipoprotein J protects cardiomyocytes from lipid-mediated inflammation and cytotoxicity induced by the epicardial adipose tissue of diabetic patients

    Artículo :116779

    Núria Puig, José Rives, Pedro Gil-Millan, Inka Miñambres, Antonino Ginel, Manel Tauron, Anna Bonaterra-Pastra, Mar Hernández-Guillamon, Antonio Pérez, José Luís Sánchez-Quesada, Sonia Benitez

    Resumen Resumen Esquema Esquema   
  • ·Ketotifen counteracts cisplatin-induced acute kidney injury in mice via targeting NF-κB/NLRP3/Caspase-1 and Bax/Bcl2/Caspase-3 signaling pathways

    Artículo :116797

    Shokooh Mohtadi, Maryam Salehcheh, Mohammad Reza Tabandeh, Layasadat Khorsandi, Mohammad Javad Khodayar

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  • ·Antioxidant and anti-Alzheimer's disease activities of 1,8-cineole and its cyclodextrin inclusion complex

    Artículo :116784

    Xin Tan, Rui Xu, Ai-Pei Li, Dan Li, Yun Wang, Qian Zhao, Li-Ping Long, Yu-Zhou Fan, Chen-Xiao Zhao, Yan Liu, Sheng-Hong Li

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  • ·Contribution of human organic anion transporter 3-mediated transport of a major linezolid metabolite, PNU-142586, in linezolid-induced thrombocytopenia

    Artículo :116801

    Danni Wang, Kenji Ikemura, Tsubasa Hasegawa, Fumihiro Yamane, Masahiro Okuda

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  • ·Interventional effects of Pueraria oral liquid on T2DM rats and metabolomics analysis

    Artículo :116780

    Hong-Bo Yang, Jie-Yu Song, Chan Xu, Jin Li, Chan Zhang, Sun Xie, Chun-li Teng

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  • ·Monastrol suppresses invasion and metastasis in human colorectal cancer cells by targeting fascin independent of kinesin-Eg5 pathway

    Artículo :116785

    Begoña Alburquerque-González, Silvia Montoro-García, Ángel Bernabé-García, Manuel Bernabé-García, Priscila Campioni-Rodrigues, Alejandro Rodríguez-Martínez, Irene Luque, Tuula Salo, Alfonso Pérez-Garrido, Horacio Pérez-Sánchez, María Luisa Cayuela, Ginés Luengo-Gil, Enrico Luchinat, Fatima Postigo-Corrales, Tommaso Staderini, Francisco José Nicolás, Pablo Conesa-Zamora

    Resumen Resumen Esquema Esquema   
  • ·PD-1-CD28-enhanced receptor and CD19 CAR-modified tumor-infiltrating T lymphocytes produce potential anti-tumor ability in solid tumors

    Artículo :116800

    Xinfeng Chen, Xuan Zhao, Xiaoning Mou, Jie Zhao, Zhen Zhang, Xudong Zhang, Jianmin Huang, Yanfen Liu, Feng Wang, Mingzhi Zhang, Liping Wang, Weiyue Gu, Yi Zhang

    Resumen Resumen Esquema Esquema   
  • ·Novel therapeutic perspectives for wet age-related macular degeneration: RGD-modified liposomes loaded with 2-deoxy-D-glucose as a promising nanomedicine

    Artículo :116776

    XiRui Chen, SiWei Liu, MoXin Chen, Ni Ni, Rong Zhou, YiQi Wang, Yang Xu, YuanHui Wang, HuiQin Gao, DanDan Zhang, ZhiMin Tang, Qin Shu, Jing Zhang, Lin Li, YaHan Ju, Ping Gu

    Resumen Resumen Esquema Esquema   

• Short Communications

  • ·Controlling autoimmune diabetes onset by targeting Protease-Activated Receptor 2

    Artículo :116622

    Gal Reches, Lynn Khoon, Narmeen Ghanayiem, Assaf Malka, Ron Piran

    Resumen Resumen Esquema Esquema   

• Corrigendum

  • ·Corrigendum to “miR-196b inhibits cell migration and invasion through targeting MAP3K1 in hydatidiform mole” [Biomed. Pharmacother. 113 (2019) 108760]

    Artículo :116634

    Zhenzhen Guo, Linlin Sui, Jia Qi, Qiannan Sun, Yuefei Xu, Na Zou, Yunpeng Xie, Ying Kong

     
  • ·Corrigendum to “Pharmacokinetic considerations for enhancing drug repurposing opportunities of anthelmintics: Niclosamide as a case study” [Biomed. Pharmacother. 173 (2024) 116394]

    Artículo :116639

    Jeong In Seo, Geun-woo Jin, Hye Hyun Yoo

    
  • ·Corrigendum to “Novel clinical phenotypes, drug categorization, and outcome prediction in drug-induced cholestasis: Analysis of a database of 432 patients developed by literature review and machine learning support” [Biomed. Pharmacother. 174 (2024) 116530]

    Artículo :116813

    Marta Moreno-Torres, Ernesto López-Pascual, Anna Rapisarda, Guillermo Quintás, Annika Drees, Inger-Lise Steffensen, Thomas Luechtefeld, Eva Serrano-Candelas, Marina Garcia de Lomana, Domenico Gadaleta, Hubert Dirven, Mathieu Vinken, Ramiro Jover

    

• Retractions

  • ·Retraction notice to "Strigol1/albumin/chitosan nanoparticles decrease cell viability, induce apoptosis and alter metabolomics profile in HepG2 cancer cell line" [Biomed. Pharmacother. 142 (2021) 111960]

    Artículo :116696

    Abdulrahman L. Al-Malki, Ashraf Bakkar, Etimad A. Huwait, Elie K. Barbour, Kalid O. Abulnaja, Taha A. Kumosani, Said S. Moselhy

    
  • ·Retraction notice to “Physcion blocks cell cycle and induces apoptosis in human B cell precursor acute lymphoblastic leukemia cells by downregulating HOXA5” [Biomed. Pharmacother. 94 (2017) 850–857]

    Artículo :116712

    Fei Gao, Wenjun Liu, Qulian Guo, Yongqi Bai, Hong Yang, Hongying Chen