Índice

• • ·Climate change and skin cancer: urgent call for action

    Página :823

     
• • ·Aspartame: it is the risk that matters, not the hazard

    Página :824-825

    Kevin McConway

     
• • ·2020 cancer incidence data in the USA reveal effects of the COVID-19 pandemic

    Página :825-826

    Julie S Townsend

     
• • ·Improving functional outcomes for patients with head and neck cancer

    Página :827-828

    Sandra Nuyts

     
• • ·Decentralised, point-of-care CAR-T for multiple myeloma

    Página :828-830

    Sébastien Anguille, Laurens Krekelbergh

     
• • ·Artificial intelligence for breast cancer screening: breathtaking results and a word of caution

    Página :830-832

    Nereo Segnan, Antonio Ponti

     
• • ·Retraction and republication—Atezolizumab, vemurafenib, and cobimetinib in patients with melanoma with CNS metastases (TRICOTEL): a multicentre, open-label, single-arm, phase 2 study

    Página :832

    The Editors of The Lancet Oncology

    
• • ·Common Sense Oncology: outcomes that matter

    Página :833-835

    Christopher M Booth, Manju Sengar, Aaron Goodman, Brooke Wilson, Ajay Aggarwal, Scott Berry, David Collingridge, Avram Denburg, Elizabeth A Eisenhauer, Ophira Ginsburg, Daniel Goldstein, Sanjeeva Gunasekera, Nazik Hammad, Kazunori Honda, Christopher Jackson, Deme Karikios, Kevin Knopf, Rachel Koven, Bernard L Marini, Deborah Maskens, Fabio Y Moraes, Ghulam Rehman Mohyuddin, Bishesh Sharma Poudyal, C S Pramesh, Felipe Roitberg, Fidel Rubagumya, Sally Schott, Bhawna Sirohi, Enrique Soto-Perez-de-Celis, Richard Sullivan, Ian F Tannock, Dario Trapani, Michelle Tregear, Winette van der Graaf, Verna Vanderpuye, Bishal Gyawali

     
• • ·Establishing a Lancet Oncology Commission on the humanitarian crisis of cancer

    Página :835-837

    Gary Rodin, Mac Skelton, Nirmala Bhoo-Pathy, Omar Dewachi, Madeline Li, Dario Trapani, Elizabeth Smyth, Matthew Banegas, Naveen Salins, Karla Unger-Saldaña, Camilla Zimmermann, Richard Sullivan

     
• • ·Radical cystectomy vs trimodality therapy for muscle-invasive bladder cancer: further extensive evaluation needed

    Página :e324

    Rahul Jena, Rami Issa, Matthew Perry

    
• • ·Radical cystectomy vs trimodality therapy for muscle-invasive bladder cancer: further extensive evaluation needed – Authors’ reply

    Página :e325

    Alexandre R Zlotta, Katherine Lajkosz, Jason A Efstathiou

    
• • ·Retraction and republication—TRICOTEL: defining symptomatic brain metastases in clinical trials

    Página :e327

    Reinhard Dummer, Hussein Tawbi

    
• • ·Correction to Lancet Oncol 2023; 24: 611–23

    Página :e328

    
• • ·Correction to Lancet Oncol 2023; 24: 868–80

    Página :e328

    
• • ·Correction to Lancet Oncol 2023; published online July 13. https://doi.org/10.1016/S1470-2045(23)00342-X

    Página :e328

    
• • ·Middle-age lung screening for everyone who has smoked

    Página :838

    Elizabeth Gourd

     
• • ·Biomarker tests for targeted oncology therapies pose tricky regulatory challenges

    Página :839

    Kathryn Senior

     
• • ·NCRI stuns cancer trial researchers with closure announcement

    Página :840

    Emma Wilkinson

     
• • ·Improving cancer outcomes in low-income areas in the USA

    Página :841

    Munyaradzi Makoni

     
• • ·NHS England ends treatment break rule in bowel cancer

    Página :842

    Kathryn Senior

     
• • ·US Supreme Court ruling on affirmative action impacts oncology

    Página :843

    Manjulika Das

     
• • ·Projected rise in cancer cases in France

    Página :844

    Barbara Casassus

     
• • ·Egypt launches 100 Healthy Days health-care campaign

    Página :845

    Manjulika Das

     
• • ·UK–BioNTech partnership for mRNA cancer vaccines

    Página :846

    Emma Wilkinson

     
• • ·South Korea backs Japanese plan to release Fukushima waste water

    Página :847

    Manjulika Das

     
• • ·Carcinogenicity of aspartame, methyleugenol, and isoeugenol

    Página :848-850

    Elio Riboli, Frederick A Beland, Dirk W Lachenmeier, M Matilde Marques, David H Phillips, Eva Schernhammer, Abdul Afghan, Ricardo Assunção, Giovanna Caderni, J Christopher Corton, Gisela de Aragão Umbuzeiro, Daphne de Jong, Melanie Deschasaux-Tanguy, Allison Hodge, Junko Ishihara, Dan D Levy, Daniele Mandrioli, Marjorie L McCullough, Sarah A McNaughton, Takeshi Morita, Anne P Nugent, Kumiko Ogawa, Arun R Pandiri, Consolato M Sergi, Mathilde Touvier, Luoping Zhang, Lamia Benbrahim-Tallaa, Shirisha Chittiboyina, Danila Cuomo, Nathan L DeBono, Charlotte Debras, Aline de Conti, Fatiha El Ghissassi, Emma Fontvieille, Rhea Harewood, John Kaldor, Heidi Mattock, Elisa Pasqual, Gabrielle Rigutto, Hannah Simba, Eero Suonio, Susana Viegas, Roland Wedekind, Mary K Schubauer-Berigan, Federica Madia

    
• • ·Growing liver cancer death rates in the UK call for healthier lifestyle choices

    Página :e329

    Elizabeth Gourd

     
• • ·NHS embraces AI-assisted radiotherapy technology

    Página :e330

    Kathryn Senior

     
• • ·ICGC ARGO precision medicine: genomic profiling-informed prediction of immunotherapy response in two patients with metastatic head and neck squamous cell carcinoma

    Página :851-853

    Riccardo Nocini, Luca Tondulli, Consuelo D’Ambrosio, Claudio Luchini, Andrew V Biankin, Raffaella Casolino, Aldo Scarpa, ICGC-ARGO, Michele Milella, Rita T Lawlor, Andrew V Biankin, Lincoln D Stein, Keunchil Park, Rita T Lawlor, Amber L Johns, Jan O Korbel, Nik Zeps, Mark A Rubin, Marco A Marra, Olivier Elemento, Steven Gallinger, David Tuveson, Lorenz Trumper, Raphael Koch, Aldo Scarpa, Paul Brennan, Christian Pilarsky, Sergey Nikolaev, Sun-Soo Yoon, Eun Sook Lee, Tatsuhiro Shibata, Xiaojian Wu, Jianmin Wu, Qimin Zhan, Wai Poon, Takayuki Yoshino, Khawla S. Al-Kuraya, Rosalind Eeles, Rebecca Fitzgerald, Carlos Caldas, Jean Abraham, David K Chang

    Esquema Esquema   
• • ·The post-truth anti-science era: what and who can we trust?

    Página :853-854

    Jules Morgan

     
• • ·Changes in cancer diagnoses and stage distribution during the first year of the COVID-19 pandemic in the USA: a cross-sectional nationwide assessment

    Página :855-867

    Xuesong Han, Nuo Nova Yang, Leticia Nogueira, Changchuan Jiang, Nikita Sandeep Wagle, Jingxuan Zhao, Kewei Sylvia Shi, Qinjin Fan, Elizabeth Schafer, K Robin Yabroff, Ahmedin Jemal

    Resumen Resumen Esquema Esquema   
• • ·Dysphagia-optimised intensity-modulated radiotherapy versus standard intensity-modulated radiotherapy in patients with head and neck cancer (DARS): a phase 3, multicentre, randomised, controlled trial

    Página :868-880

    Christopher Nutting, Laura Finneran, Justin Roe, Mark A Sydenham, Matthew Beasley, Shree Bhide, Cheng Boon, Audrey Cook, Emma De Winton, Marie Emson, Bernadette Foran, Robert Frogley, Imran Petkar, Laura Pettit, Keith Rooney, Tom Roques, Devraj Srinivasan, Justine Tyler, Emma Hall, DARS Trialist Group, S Oliveros, M Lei, N Palaniappan, D Hwang, R Shanmugasundaram, G Cogill, C Wilson, S Brennan, J Christian, N Cole, C Macgregor

    Resumen Resumen Esquema Esquema   
• • ·Pembrolizumab plus lenvatinib as first-line therapy for advanced non-clear-cell renal cell carcinoma (KEYNOTE-B61): a single-arm, multicentre, phase 2 trial

    Página :881-891

    Laurence Albiges, Howard Gurney, Vagif Atduev, Cristina Suarez, Miguel A Climent, David Pook, Piotr Tomczak, Philippe Barthelemy, Jae Lyun Lee, Viktor Stus, Thomas Ferguson, Pawel Wiechno, Erhan Gokmen, Louis Lacombe, Craig Gedye, Rodolfo F Perini, Manish Sharma, Xiang Peng, Chung-Han Lee

    Resumen Resumen Esquema Esquema   
• • ·Pembrolizumab in patients with rare and ultra-rare sarcomas (AcSé Pembrolizumab): analysis of a subgroup from a non-randomised, open-label, phase 2, basket trial

    Página :892-902

    Jean-Yves Blay, Sylvie Chevret, Axel Le Cesne, Mehdi Brahmi, Nicolas Penel, Sophie Cousin, Francois Bertucci, Emmanuelle Bompas, Thomas Ryckewaert, Pauline Soibinet, Pascaline Boudou-Rouquette, Esma Saada Bouzid, Patrick Soulie, Thibaud Valentin, Jean-Pierre Lotz, Diego Tosi, Zoé Neviere, Mathilde Cancel, Isabelle Ray-Coquard, Laetitia Gambotti, Frédéric Legrand, Assia Lamrani-Ghaouti, Clotilde Simon, Caroline Even, Christophe Massard

    Resumen Resumen Esquema Esquema   
• • ·Radiotherapy resources in Brazil (RT2030): a comprehensive analysis and projections for 2030

    Página :903-912

    Arthur Accioly Rosa, Cecília Félix Penido Mendes de Sousa, Leonardo Cunha Furbino Pimentel, Homero Lavieri Martins, Fabio Ynoe Moraes, Gustavo Nader Marta, Marcus Simões Castilho

    Resumen Resumen Esquema Esquema   
• • ·Fractionated initial infusion and booster dose of ARI0002h, a humanised, BCMA-directed CAR T-cell therapy, for patients with relapsed or refractory multiple myeloma (CARTBCMA-HCB-01): a single-arm, multicentre, academic pilot study

    Página :913-924

    Aina Oliver-Caldés, Verónica González-Calle, Valentín Cabañas, Marta Español-Rego, Paula Rodríguez-Otero, Juan Luis Reguera, Lucía López-Corral, Beatriz Martin-Antonio, Aintzane Zabaleta, Susana Inogés, Sara Varea, Laura Rosiñol, Ascensión López-Díaz de Cerio, Natalia Tovar, Raquel Jiménez, Miriam López-Parra, Luis Gerardo Rodríguez-Lobato, Andrés Sánchez-Salinas, Eulàlia Olesti, Maria Calvo-Orteu, Julio Delgado, José Antonio Pérez-Simón, Bruno Paiva, Felipe Prósper, Joaquín Sáez-Peñataro, Manel Juan, José M Moraleda, María-Victoria Mateos, Mariona Pascal, Alvaro Urbano-Ispizua, Carlos Fernández de Larrea

    Resumen Resumen Esquema Esquema   
• • ·Erdafitinib in patients with advanced solid tumours with FGFR alterations (RAGNAR): an international, single-arm, phase 2 study

    Página :925-935

    Shubham Pant, Martin Schuler, Gopa Iyer, Olaf Witt, Toshihiko Doi, Shukui Qin, Josep Tabernero, David A Reardon, Christophe Massard, Anna Minchom, Iwona Lugowska, Omar Carranza, Dirk Arnold, Martin Gutierrez, Helen Winter, Kim Stuyckens, Lauren Crow, Saltanat Najmi, Constance Hammond, Shibu Thomas, Ademi Santiago-Walker, Spyros Triantos, Hussein Sweiti, Yohann Loriot, RAGNAR Investigators, Omar Carranza, Martin Alberto Greco, Jim Coward, Anthony Joshua, Christos Karapetis, Christopher Hart, Alison Zhang, Hans Prenen, Jean-Charles Goeminne, Jean-Pascal Machiels, Sylvie Rottey, Marcelo Corassa, Graziela Zibetti Dal Molin, Katsuki Tiscoski, Denis Leonardo Fontes Jardim, Milena Mak, Wei Fu, Herui Yao, Jing Huang, Haiping Jiang, Shukui Qin, Baoshi Chen, Dong Yan, Yu Yang, Yohann Loriot, Christophe Le Tourneau, Nicolas Penel, Sébastien Salas, Jean-Yves Blay, Pierre-Emmanuel Brachet, Xavier Durando, Sheik Emambux, Alain Ravaud, Gunnar Folprecht, Dirk Arnold, Martin Schuler, Marit Ahrens, Alexander Golf, Georg Martin Haag, Florian Lordick, Alexander Desuki, Marina Cazzaniga, Fortunato Ciardiello, Michele Milella, Takafumi Koyama, Yoshiki Hirooka, Wataru Okamoto, Kenjiro Aogi, Yasutoshi Kuboki, Jungyun Lee, Sung-Bae Kim, Myung-Ju Ahn, Jong Hee Chang, Yong-Man Kim, Do-Hyun Nam, Jae-Sung Park, Iwona Lugowska, Luis Paz-Ares, Victor Moreno, Andres Cervantes, Mariona Calvo, Alejandro Falcon, Antonio Gonzalez, Josep Tabernero, Alejandro Martinez Bueno, Javier García-Corbacho, Federico Longo, Chia-Jui Yen, Jen-Shi Chen, Ming-Feng Hou, Yee Chao, Kun-Ming Rau, Tai-Jan Chiu, Yin-Hsun Feng, Chih-Hung Hsu, Wen-Tsung Huang, Kuan-Ming Lai, Su-peng Yeh, Daniel Palmer, Anna Minchom, Helen Winter, Liam Welsh, Ruth Plummer, Gopakumar Iyer, Martin Gutierrez, Mehmet Bilen, Edward Arrowsmith, Shubham Pant, David Robert Spigel, Dan Paul Zandberg, Deborah Doroshow, Christine Lu-Emerson, Mehdi Moezi, Scott Paulson, David Reardon, Patrick Ward, Jorge Chaves, Claud Grigg, Atif Hussein, Sudhir Manda, Michael Monticelli, Rubina Qamar, Stephen L Richey, David Tamura, Sharon Wilks

    Resumen Resumen Esquema Esquema   
• • ·Artificial intelligence-supported screen reading versus standard double reading in the Mammography Screening with Artificial Intelligence trial (MASAI): a clinical safety analysis of a randomised, controlled, non-inferiority, single-blinded, screening accuracy study

    Página :936-944

    Kristina Lång, Viktoria Josefsson, Anna-Maria Larsson, Stefan Larsson, Charlotte Högberg, Hanna Sartor, Solveig Hofvind, Ingvar Andersson, Aldana Rosso

    Resumen Resumen Esquema Esquema  
• • ·Designing clinical trials based on modern imaging and metastasis-directed treatments in patients with oligometastatic breast cancer: a consensus recommendation from the EORTC Imaging and Breast Cancer Groups

    Página :e331

    David Pasquier, Luc Bidaut, Daniela Elena Oprea-Lager, Nandita M deSouza, David Krug, Laurence Collette, Wolfgang Kunz, Yazid Belkacemi, Maria Grazia Bau, Caroline Caramella, Lioe-Fee De Geus-Oei, Alex De Caluwé, Christophe Deroose, Olivier Gheysens, Ken Herrmann, Isabelle Kindts, Michalis Kontos, Sherko Kümmel, Barbro Linderholm, Egesta Lopci, Icro Meattini, Ann Smeets, Orit Kaidar-Person, Philip Poortmans, Pelagia Tsoutsou, Nawale Hajjaji, Nicola Russell, Elżbieta Senkus, Jean-Noël Talbot, Lale Umutlu, Vincent Vandecaveye, Joost J C Verhoeff, Willemien Menke-van der Houven van Oordt, Helle D Zacho, Fatima Cardoso, Laure Fournier, Frederieke Van Duijnhoven, Frédéric E Lecouvet

    Resumen Resumen Esquema Esquema   
• • ·National Cancer Institute Collaborative Workshop on Shaping the Landscape of Brain Metastases Research: challenges and recommended priorities

    Página :e344

    Michelle M Kim, Minesh P Mehta, DeeDee K Smart, Patricia S Steeg, Julie A Hong, Michael G Espey, Pataje G Prasanna, Laura Crandon, Christine Hodgdon, Niki Kozak, Terri S Armstrong, Aki Morikawa, Nicole Willmarth, Kirk Tanner, Adrienne Boire, Melanie Hayden Gephart, Kim A Margolin, Jona Hattangadi-Gluth, Hussein Tawbi, Daniel M Trifiletti, Caroline Chung, Upal Basu-Roy, Robyn Burns, Isabella C Glitza Oliva, Ayal A Aizer, Carey K Anders, Joanne Davis, Manmeet S Ahluwalia, Veronica Chiang, Jing Li, Rupesh Kotecha, Silvia C Formenti, Benjamin M Ellingson, Vinai Gondi, Paul W Sperduto, Jill S Barnholtz-Sloan, Jordi Rodon, Eudocia Q Lee, Mustafa Khasraw, Debra Nana Yeboa, Priscilla K Brastianos, Evanthia Galanis, C Norman Coleman, Mansoor M Ahmed

    Resumen Resumen Esquema Esquema  
• • ·Metastatic seminoma masquerading as sarcoidosis

    Página :e355

    Kevin E Shopsowitz, Xiu Qing Wang, Maryam Soleimani, Monika Hudoba, Luke Y C Chen, Eric McGinnis