Recommendations of the French Society of Rheumatology on pharmacological treatment of knee osteoarthritis - 28/11/20
on behalf of the French Society of Rheumatologyq
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Abstract |
Objectives |
To establish recommendations for pharmacological treatment of knee osteoarthritis specific to France.
Methods |
On behalf of the French Society of Rheumatology (SFR), a bibliography group analyzed the literature on the efficacy and safety of each pharmacological treatment for knee osteoarthritis. This group joined a multidisciplinary working group to draw up recommendations. Strength of recommendation and quality of evidence level were assigned to each recommendation. A review committee gave its level of agreement.
Results |
Five general principles were established: 1) need to combine pharmacological and non-pharmacological treatments, 2) personalization of treatment, 3) symptomatic and/or functional aim of pharmacological treatments, 4) need to regularly re-assess the treatments and 5) discussion about arthroplasty if medical treatment fails.
Six recommendations involved oral treatments: 1) paracetamol should not necessarily be prescribed systematically and/or continuously, 2) NSAIDs, possibly as first-line, 3) weak opioids, 4) strong opioids, 5) symptomatic slow-acting drugs of osteoarthritis, and 6) duloxetine (off-label use). Two recommendations involved topical agents (NSAIDs and capsaicin<1%). Three recommendations involved intra-articular treatments: corticosteroid or hyaluronic acid injections that can be proposed to patients. The experts did not draw a conclusion about the benefits of platelet-rich plasma injections.
Conclusion |
These are the first recommendations of the SFR on the pharmacological treatment of knee osteoarthritis.
Le texte complet de cet article est disponible en PDF.Keywords : Knee osteoarthritis, Osteoarthritis, Treatment, Recommendations
Plan
Vol 87 - N° 6
P. 548-555 - décembre 2020 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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