Does tranexamic acid influence activated clotting time values in patients undergoing cardiac surgery? - 28/04/22
Doi : 10.1016/j.jclinane.2020.110125
Elise Bartlett, BS a, Richard D. Urman, MD d, ⁎ 
, Ivan Urits, MD b, Alan D. Kaye, MD PhD c, Omar Viswanath, MD d, e
, Ivan Urits, MD b, Alan D. Kaye, MD PhD c, Omar Viswanath, MD d, e a Pain Specialty Group, Newington, NH, United States of America
b Brigham and Women's Hospital, Department of Anesthesiology, Perioperative and Pain Medicine, Harvard Medical School, Boston, MA, United States of America
c Beth Israel Deaconess Medical Center, Department of Anesthesiology, Critical Care, and Pain Medicine, Harvard Medical School, Boston, MA, United States of America
d Louisiana State University Health Shreveport, Department of Anesthesiology, Shreveport, LA, United States of America
e Valley Anesthesiology and Pain Consultants – Envision Physician Services, Phoenix, AZ, United States of America
⁎Corresponding author at: Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Boston, MA 02115, United States of America.Department of Anesthesiology, Perioperative and Pain MedicineBrigham and Women's HospitalBostonMA02115United States of America
Highlights |
• | Activated clotting time (ACT) values after heparinization was comparable between the study groups. |
• | ACT values after protamine was comparable between the TXA group and the control group. |
• | TXA did not influence heparin dose in adult patients. |
• | TXA did not influence protamine dose in adult patients. |
• | TXA administration significantly reduced postoperative blood loss and transfusion requirements in cardiac surgical patients. |
Plan
© 2020
Elsevier Inc. Tous droits réservés.
Vol 79
Article 110125- août 2022 Retour au numéro
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