Diaphragmatic weakness related to radiotherapy: 2 cases and a review - 05/10/22
Abstract |
Post-radiation diaphragmatic weakness have rarely been described. We report two cases of post-radiation diaphragmatic weakness from our center, and review the other published cases, computing clinical, electromyography and magnetic resonance imaging data. Including our two cases, seven cases of post-radiation diaphragmatic weakness have been described. Most occurred after mantle-field radiotherapy for Hodgkin lymphoma (5/7), often in associations with chemotherapy (4/7). Other radiations-induced complications were found (5/7) such as brachial plexopathy, cardiac involvement or hypothyroidy. When studied, phrenic nerve conduction studies revealed different profiles, from clearly abnormal responses to limit amplitudes. Imaging can be a useful diagnostic tool, displaying abnormalities with sharp limits matching the radiation field. Data is limited about long-term evolution. Presentation of post-radiation diaphragmatic weakness seems relatively homogeneous. We propose a diagnosis work-up for post-radiation diaphragmatic weakness, to exclude potentially treatable differential diagnoses.
Le texte complet de cet article est disponible en PDF.Keywords : Respiratory failure, Radiotherapy, Radiation, Electrodiagnosis, Magnetic resonance imaging
Plan
Vol 178 - N° 8
P. 796-801 - octobre 2022 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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