Cessation of asthma medication in early pregnancy - 18/08/11
Reprint requests: Tina V. Hartert, MD, MPH, Center for Lung Research, Center for Health Services Research, T-1218 MCN, Vanderbilt University School of Medicine, Nashville, TN 37232-2650.Abstract |
Objective |
The objective of the study was to determine whether women alter their use of asthma medications during pregnancy.
Study design |
Weekly asthma medication use was determined from prescription claims data in a cohort of 112,171 pregnant women aged 15 to 44 years who were continuously enrolled in the Tennessee Medicaid program prior to their singleton pregnancy and who delivered a singleton birth during 1995 to 2001. Change in asthma medication use was evaluated using generalized estimating equation analyses.
Results |
Women with asthma significantly (P ≤ 0.0005) decreased their asthma medication use from 5 to 13 weeks of pregnancy. During the first trimester, there was a 23% decline in inhaled corticosteroid prescriptions, a 13% decline in short-acting beta-agonist prescriptions, and a 54% decline in rescue corticosteroid prescriptions.
Conclusions |
Utilization of all categories of asthma medications decreased in early pregnancy, with the largest declines occurring for inhaled and rescue corticosteroids.
Le texte complet de cet article est disponible en PDF.Key words : Asthma, Pregnancy, Medicaid database, Drug utilization, Guidelines
Plan
| Supported in part by research grants UO1 HL 72471, MO1 RR00095, and KO8 AI01582, Agency for Healthcare Research and Quality, Centers for Education and Research Grant U18-HS10384, Geriatric Research Education and Clinical Center, Department of Veterans Affairs, and the Food and Drug Administration FD-U-000073. |
Vol 195 - N° 1
P. 149-153 - juillet 2006 Retour au numéro
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