Reconstructive strategies following surgical resection of malignant sublingual gland tumors: A single institution experience - 08/05/24

Doi : 10.1016/j.jormas.2024.101908

Shi-Long Zhang ^a,^b,^{^{#
These authors contributed equally to this work as co-first authors.}}, Ning Xu ^c,^{^{#
These authors contributed equally to this work as co-first authors.}}, Chun- Bo Dou ^a,^b, Liang Mao ^a,^d, Si-Rui Ma ^a,^d, Jun Jia ^a,^d,^⁎ , Zi-Li Yu ^a,^d,^⁎
^a Department of Oral and Maxillofacial Surgery, School and Hospital of Stomatology, Wuhan University, 430079 Wuhan, China
^b Dongfeng Stomatological Hospital, Hubei University of Medicine, 442000, Shiyan, China
^c Department of Oral and Maxillofacial Surgery, Jining Stomatological Hospital, 272000, Jining, China
^d State Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, Key Laboratory of Oral Biomedicine Ministry of Education, Hubei Key Laboratory of Stomatology, School & Hospital of Stomatology, Wuhan University, 430079 Wuhan, China

^⁎Corresponding authors.

En prensa. Pruebas corregidas por el autor. Disponible en línea desde el Wednesday 08 May 2024

Abstract

Objective

To investigate the characteristics and treatment modalities of malignant tumors originating from the sublingual gland, as well as evaluate the therapeutic outcomes following free flap reconstruction.

Methods

A retrospective statistical analysis was conducted on the clinical data of nine patients diagnosed with malignant neoplasms tumor of the sublingual gland.

Results

Nine case of malignant tumors originated from the sublingual glandular tissue, encompassing eight adenoid cystic carcinoma (ACC) and a single case of bipartite differentiated carcinoma—a hybrid of epithelial-myoepithelial carcinoma and adenoid cystic carcinoma. Among the nine patients, four anterolateral thigh flaps were used (three of which were thin flaps), and five forearm flaps were also empoyed. The size of flaps varied, with the lengths ranging from 4 cm to 9 cm, and the widths ranging from 2.5 cm to 6 cm. The vessels chosen for anastomosis were the superior thyroid artery in seven cases, the facial artery in one case, and the lingual artery in one case. Among the eight patients who underwent dissection of cervical lymph nodes, metastasis were found in one case. Two patients underwent adjuvant radiotherapy. Upon postoperative follow-up, there was no recurrence in any of the nine patients .