Ectoparasites : Scabies - 11/02/20

Doi : 10.1016/j.jaad.2019.05.109

Cristina Thomas, MD ^a, Sarah J. Coates, MD ^b, Daniel Engelman, MD ^c,^d,^e,^f, Olivier Chosidow, MD ^c,^g, Aileen Y. Chang, MD ^b,^c,^⁎
^a Departments of Dermatology and Internal Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts
^b Department of Dermatology, University of California, San Francisco, San Francisco, California
^c International Alliance for the Control of Scabies, Parkville, Australia
^d Tropical Diseases, Murdoch Children's Research Institute, Melbourne, Australia
^e Department of Paediatrics, University of Melbourne, Melbourne, Australia
^f Department of General Medicine, Royal Children's Hospital, Melbourne, Australia
^g Department of Dermatology, Assistance Publique – Hôpitaux de Paris, University Paris-Est Créteil, Créteil, France

^∗Reprint requests: Aileen Y. Chang, MD, University of California San Francisco, Department of Dermatology, Zuckerberg San Francisco General, Hospital and Trauma Center, 1001 Potrero Ave, Building 90, Ward 92, San Francisco, CA 94110.University of California San FranciscoDepartment of DermatologyZuckerberg San Francisco GeneralHospital and Trauma Center1001 Potrero Ave, Building 90, Ward 92San FranciscoCA94110

Abstract

Scabies is an ectoparasitic dermatosis caused by Sarcoptes scabiei var. hominis and is a public health issue in all countries regardless of socioeconomic status. In high-income countries, delays in diagnosis can lead to institutional outbreaks; in low- and middle-income countries, poor access to health care contributes to disease undertreatment and long-term systemic sequelae. With scabies now recognized as a neglected tropical disease by the World Health Organization, increased awareness and systematic efforts are addressing gaps in diagnosis and treatment that impede scabies control. This review summarizes the available data and provides an update on scabies epidemiology, clinical features, diagnosis, management, and public health considerations.

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Key words : crusted scabies, homeless, impetigo, infestation, ivermectin, mass drug administration, neglected tropical disease, optical coherence tomography, permethrin, poststreptococcal glomerulonephritis, pruritus, reflectance confocal microscopy, refugee, rheumatic fever, rheumatic heart disease, Sarcoptes scabiei, scabies, Staphylococcus aureus, Streptococcus pyogenes

Abbreviations used : APSGN, DALY, MDA, RCM

Esquema

Epidemiology

Clinical features

Classic scabies

Atypical scabies and subpopulations

Local complications

Systemic complications

Novel systemic treatments

Novel topical agents

Environmental measures

Public health considerations

Reporting and surveillance

Institutional outbreaks

Mass drug administration

Scabies as a World Health Organization neglected tropical disease

	Funding sources: None.
	Dr Chosidow has received speaker fees and research support from Codexial Dermatologie, research support from Merck Sharp & Dohme, and speaker fees from Zambon. Drs Thomas, Coates, Engelman, and Chang have no conflicts of interest to disclose.
	Date of release: March 2020
	Expiration date: March 2023