Dark tea extracts: Chemical constituents and modulatory effect on gastrointestinal function - 27/10/20
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Highlights |
• | Differences in major chemical constituents existed in different dark teas. |
• | Dark tea promoted gastrointestinal transit in normal mice. |
• | Dark tea restored antibiotic-induced dysbiosis of intestinal microflora. |
Abstract |
Processing of dark tea varieties, such as Fu brick tea, Liupao tea, Qianliang tea, and Qing brick tea, includes solid-state fermentation involving microorganisms. In this study, we analyzed the major chemical constituents of dark tea extracts and evaluated their modulatory effect on the gastrointestinal function in normal mice, including the improvement of gastrointestinal transit and intestinal microbial, as well as the attenuation of intestinal microbial dysbiosis and intestinal pathological damage, and the adjustment of immune function in antibiotic-treated mice. Substantial differences in major chemical constituents, including total polyphenols, total organic acids, water extract content, 18 free amino acids, gallic acid, and six tea catechins, were observed among Fu brick tea, Qianliang tea, Qing brick tea, and Liupao tea extracts. Extracts from the four dark tea varieties significantly promoted gastrointestinal transit and colonization of beneficial Bifidobacterium and Lactobacillus, and inhibited the growth of harmful Escherichia coli and Enterococcus in normal mice. In addition, Qianliang tea, Qing brick tea, and Liupao tea extracts significantly accelerated the reversal of the ampicillin sodium-induced pathological damage in the ileum, intestinal bacterial dysbiosis (Bifidobacterium, Lactobacillus, E. coli, and Enterococcus), and low immunity.
El texto completo de este artículo está disponible en PDF.Abbreviations : AT, EC, ECG, EGC, EGCG, GCG, H&E, HFB, HL, HQ, HQB, IL-2, LFB, LL, LQ, LQB, MFB, ML, MQ, MQB, NC, NO, sIgA, SR
Keywords : Dark tea, Gastrointestinal function, Gastrointestinal transit, Antibiotic, Restoration, Intestinal microbes
Esquema
Vol 130
Artículo 110514- octobre 2020 Regresar al númeroBienvenido a EM-consulte, la referencia de los profesionales de la salud.
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