Biological factors predicting the length of hospital stay in odontogenic cellulitis - 22/07/21

Doi : 10.1016/j.jormas.2021.07.007

Louis Bègue ^a, Matthias Schlund ^b, Gwénaël Raoul ^b, Joël Ferri ^b, Ludovic Lauwers ^a, Romain Nicot ^b,^⁎
^a University Lille, Department of Oral and Maxillofacial Surgery, CHU Lille, F-59000 Lille, France
^b University Lille, Department of Oral and Maxillofacial Surgery, CHU Lille, INSERM U 1008, Controlled Drug Delivery Systems and Biomaterials, F-59000 Lille, France

^⁎Correspondence to: Service de Chirurgie Maxillo Faciale et Stomatologie Hôpital Roger Salengro Bd du Prof Emile Laine, 59037 Lille-Cedex, France.Service de Chirurgie Maxillo Faciale et Stomatologie Hôpital Roger Salengro Bd du Prof Emile LaineLille-Cedex59037France

En prensa. Pruebas corregidas por el autor. Disponible en línea desde el Thursday 22 July 2021
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Abstract

Objective

The purpose of this study was to assess whether common biological factors are correlated with a longer hospital stay.

Study Design

All patients having odontogenic cellulitis, treated from January 2019 to December 2019 at Lille University Hospital, and requiring surgical drainage under general anesthesia, were included, retrospectively. Data, such as length of hospital stay and biological factors, namely, C-reactive protein (CRP) level, Laboratory Risk Indicator for Necrotizing Fasciitis (LRINEC) score, and bacterial samples were collected.

Results

Significant moderate-strong correlations were found between postoperative length of stay and patients’ LRINEC score (r_s = 0.556) and presurgical CRP level (r_s = 0.579). There was a significant moderate correlation between postoperative length of stay and presurgical procalcitonin level (r_s = 0.451), and a weak correlation between postoperative length of stay and presurgical white blood cell count (r_s = 0.282). Linear regression verified CRP as an independent predictor of length of hospital stay, showing a significant linear relationship between them (p < 0.0001). A significant regression equation was found (F(1,65) = 27.089; p = 0.0001), with an R² of 0.294.

Conclusion

In this study, CRP was the key biological predictor of length of hospital stay.

Statement of clinical relevance

The ability to predict length of hospital stay and identify patients requiring intensive care management, using simple and inexpensive biological parameters (such as CRP), will enable more cost-effective care and efficient hospital bed management.

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Keywords : Odontogenic infection, Odontogenic cellulitis, Length of hospital stay, Hospitalization duration, C-reactive protein, White blood cell count