Diagnostic performance of artificial intelligence for histologic melanoma recognition compared to 18 international expert pathologists - 17/02/22
Doi : 10.1016/j.jaad.2021.02.009
Titus J. Brinker, MD a, ⁎ 
, Max Schmitt, MSc a, Eva I. Krieghoff-Henning, PhD a, Raymond Barnhill, MD b, Helmut Beltraminelli, MD c, Stephan A. Braun, MD d, e, Richard Carr, MD f, Maria-Teresa Fernandez-Figueras, MD g, Gerardo Ferrara, MD h, Sylvie Fraitag, MD i, Raffaele Gianotti, MD j, Mar Llamas-Velasco, MD k, Cornelia S.L. Müller, MD l, Antonio Perasole, MD m, Luis Requena, MD n, o, Omar P. Sangueza, MD p, Carlos Santonja, MD n, Hans Starz, MD q, Esmeralda Vale, MD r, Wolfgang Weyers, MD s, Achim Hekler, Dipl-Inform a, Jakob N. Kather, MD t, u, Stefan Fröhling, MD u, Dieter Krahl, MD v, Tim Holland-Letz, PhD w, Jochen S. Utikal, MD x, y, Andrea Saggini, MD z, Heinz Kutzner, MD z
, Max Schmitt, MSc a, Eva I. Krieghoff-Henning, PhD a, Raymond Barnhill, MD b, Helmut Beltraminelli, MD c, Stephan A. Braun, MD d, e, Richard Carr, MD f, Maria-Teresa Fernandez-Figueras, MD g, Gerardo Ferrara, MD h, Sylvie Fraitag, MD i, Raffaele Gianotti, MD j, Mar Llamas-Velasco, MD k, Cornelia S.L. Müller, MD l, Antonio Perasole, MD m, Luis Requena, MD n, o, Omar P. Sangueza, MD p, Carlos Santonja, MD n, Hans Starz, MD q, Esmeralda Vale, MD r, Wolfgang Weyers, MD s, Achim Hekler, Dipl-Inform a, Jakob N. Kather, MD t, u, Stefan Fröhling, MD u, Dieter Krahl, MD v, Tim Holland-Letz, PhD w, Jochen S. Utikal, MD x, y, Andrea Saggini, MD z, Heinz Kutzner, MD z a Digital Biomarkers for Oncology Group, German Cancer Research Center (DKFZ), Heidelberg, Germany
b Departments of Pathology and Translational Research, Institut Curie, Paris, France
c Department of Dermatology, Inselspital Bern University Hospital, University of Bern, Bern, Switzerland
d Department of Dermatology, Medical Faculty, Heinrich-Heine-University, Düsseldorf, Germany
e Department of Dermatology, University of Münster, Münster, Germany
f Department of Pathology, Warwick Hospital, Warwick, United Kingdom
g University General Hospital of Catalonia, Grupo Quironsalud, International University of Catalonia, Sant Cugat del Vallés, Barcelona, Spain
h Anatomic Pathology Unit, Macerata General Hospital, Macerata, Italy
i Department of Pathology, University Paris Descartes, Necker-Enfants Malades Hospital, Assistance Publique Hospitals of Paris, Paris, France
j Dermatopathology Lab, Dermatological Clinic, University of Milan, Milan, Italy
k Department of Dermatology, University Hospital La Princesa, Madrid, Spain
l Department of Dermatology, Venereology and Allergology, Saarland University Medical Center, Homburg/Saar, Germany
m Anatomic and Cytopathology, Az. ULSS 8 Berica, Regione Veneto, Ospedale San Bortolo, Vicenza, Italy
n Dermatology Department, Fundación Jiménez Díaz, Autonomous University of Madrid, Madrid, Spain
o Anatomic Pathology Service, Fundación Jiménez Díaz, Madrid, Spain
p Dermatopathology, Wake Forest School of Medicine, Winston-Salem, North Carolina
q Dermpath München, Munich, Germany
r Service of Dermatology, Medical-Surgical Center Lisbon, Lisbon, Portugal
s Center for Dermatopathology, Freiburg, Germany
t Department of Medicine III, University Hospital RWTH Aachen, Aachen, Germany
u National Center for Tumor Diseases (NCT), German Cancer Research Center (DKFZ), Heidelberg, Germany
v Dres. Krahl Dermatopathology, Heidelberg, Germany
w Division of Biostatistics, German Cancer Research Center (DKFZ), Heidelberg, Germany
x Skin Cancer Unit, German Cancer Research Center (DKFZ), Heidelberg, Germany
y Department of Dermatology, Venereology and Allergology, University Medical Center Mannheim, Ruprecht-Karl University of Heidelberg, Mannheim, Germany
z Dermatopathology Friedrichshafen, Friedrichshafen, Germany
∗Correspondence to: Titus J. Brinker, Digital Biomarkers for Oncology Group, German Cancer Research Center, im Neuenheimer Feld 460, Heidelberg, 69120, GermanyDigital Biomarkers for Oncology GroupGerman Cancer Research Centerim Neuenheimer Feld 460Heidelberg69120Germany
| Funding sources: This work was supported by the German Federal Ministry of Health, Berlin, Germany [grant: Skin-Classification-Project to TJB; German Cancer Research Center]. |
|
| IRB approval status: Ethics approval was obtained from the ethics committee of the Medical Faculty of Mannheim of the University of Heidelberg, 68131 Mannheim, Germany, before the study was initiated. |
|
| Reprints not available from the authors. |
© 2021
American Academy of Dermatology, Inc.. Publicado por Elsevier Masson SAS. Todos los derechos reservados.
Vol 86 - N° 3
P. 640-642 - mars 2022 Regresar al número
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