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Early pacemaker insertion after aortic valve replacement with an Edwards Intuity sutureless valve - 10/11/22

Doi : 10.1016/j.acvd.2022.05.007 
Alexis Mechulan a, , Raphaël Demoulin b, Pierre Dieuzaide a, Angélique Peret a, Alain Vaillant c, Jacques Vicat c, Ahmed Bouharaoua a, Elisabeth Leude-Vaillant c, Alain Cornen c, Sébastien Prevot a
a Service de cardiologie, Ramsay Santé, hôpital privé Clairval, 13009 Marseille, France 
b Service de cardiologie, hôpital d’instruction des armées Sainte-Anne, 83800 Toulon, France 
c Service de chirurgie cardiaque, Ramsay Santé, hôpital privé Clairval, 13009 Marseille, France 

Corresponding author.

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Graphical abstract

Central illustration. Increase in pacemaker insertion and new bundle branch block (BBB) in patients implanted with an Intuity valve compared with those who received a standard surgical aortic valve.

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Highlights

The rate of early pacemaker insertion was significantly higher in patients who received an Intuity sutureless aortic valve in comparison to those who received a standard bioprosthetic aortic valve.
The main indications for pacemaker insertion were complete atrioventricular block and left bundle branch block with prolongation of the HV interval.
The rate of new postoperative left bundle branch block conduction disorders was significantly higher in patients implanted with an Intuity valve.

El texto completo de este artículo está disponible en PDF.

Abstract

Background

Postoperative conduction disorders are serious adverse events in patients undergoing aortic valve replacement, and may prolong the duration of hospitalization and require pacemaker insertion.

Aim

Our aim was to evaluate the rate of pacemaker insertion after implantation of an Edwards Intuity sutureless aortic valve (Edwards Lifesciences, Irvine, CA, USA) compared with a standard surgical bioprosthesis.

Methods

This retrospective single-centre study included patients who underwent aortic valve replacement with an Intuity sutureless aortic valve or a standard bioprosthetic valve between 4 June 2014 and 27 June 2016. The main outcome criterion was the rate of postoperative pacemaker insertion. Secondary outcome criteria included the rate of new conduction disorders, the rate of atrial arrhythmia or paroxysmal conduction disorders, mortality and duration of hospital stay.

Results

Ninety-three patients received an Intuity sutureless aortic valve (median age 76 years, interquartile range 71–80 years), and 176 were implanted with a standard biological aortic valve (median age 73 years, interquartile range 68–79 years; P=0.007). The rate of postoperative pacemaker insertion, after adjustment, was 22.44% in the Intuity group and 5.66% in the standard aortic valve group (P=0.030). The main indications for postoperative pacemaker insertion were complete atrioventricular block and left bundle branch block with prolongation of the H-V interval. The rate of new postoperative left bundle branch block conduction disorders was significantly higher in patients implanted with an Intuity valve (odds ratio 5.28, 95% confidence interval 1.59 to 23.05; P=0.012).

Conclusion

Higher rates of pacemaker insertion and new conduction disorders were observed in patients implanted with an Intuity sutureless bioprosthesis compared with those who received a standard surgical aortic valve.

El texto completo de este artículo está disponible en PDF.

Keywords : Aortic valve replacement, Atrioventricular block, Bundle branch block, Sutureless valve, Pacemaker

Abbreviations : AoVR, AVB, BBB, CI, IQR, OR, TAVI


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© 2022  The Authors. Publicado por Elsevier Masson SAS. Todos los derechos reservados.
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Vol 115 - N° 10

P. 490-495 - octobre 2022 Regresar al número
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