Wearable electrocardiogram devices in patients with congenital long QT syndrome: The SMART-QT study - 01/06/24
Bienvenido a EM-consulte, la referencia de los profesionales de la salud.
Artículo gratuito.
Conéctese para beneficiarse!
Graphical abstract |
Highlights |
• | Two wearable ECG devices were evaluated in patients with congenital LQTS. |
• | The various genotypes and ST-T wave patterns seen in this disease were represented. |
• | The QTc and ST-T wave patterns obtained with these devices were correlated with the ECG. |
Abstract |
Background |
In patients with congenital long QT syndrome (LQTS), the risk of ventricular arrhythmia is correlated with the duration of the corrected QT interval and the changes in the ST-T wave pattern on the 12-lead surface electrocardiogram (12L-ECG). Remote monitoring of these variables could be useful.
Aim |
To evaluate the abilities of two wearable electrocardiogram devices (Apple Watch and KardiaMobile 6L) to provide reliable electrocardiograms in terms of corrected QT interval and ST-T wave patterns in patients with LQTS.
Methods |
In a prospective multicentre study (ClinicalTrials.gov identifier: NCT04728100), a 12L-ECG, a 6-lead KardiaMobile 6L electrocardiogram and two single-lead Apple Watch electrocardiograms were recorded in patients with LQTS. The corrected QT interval and ST-T wave patterns were evaluated manually.
Results |
Overall, 98 patients with LQTS were included; 12.2% were children and 92.8% had a pathogenic variant in an LQTS gene. The main genotypes were LQTS type 1 (40.8%), LQTS type 2 (36.7%) and LQTS type 3 (7.1%); rarer genotypes were also represented. When comparing the ST-T wave patterns obtained with the 12L-ECG, the level of agreement was moderate with the Apple Watch (k=0.593) and substantial with the KardiaMobile 6L (k=0.651). Regarding the corrected QT interval, the correlation with 12L-ECG was strong for the Apple Watch (r=0.703 in lead II) and moderate for the KardiaMobile 6L (r=0.593). There was a slight overestimation of corrected QT interval with the Apple Watch and a subtle underestimation with the KardiaMobile 6L.
Conclusions |
In patients with LQTS, the corrected QT interval and ST-T wave patterns obtained with the Apple Watch and the KardiaMobile 6L correlated with the 12L-ECG. Although wearable electrocardiogram devices cannot replace the 12L-ECG for the follow-up of these patients, they could be interesting additional monitoring tools.
El texto completo de este artículo está disponible en PDF.Keywords : Long QT syndrome, QT interval, Remote monitoring, Smartwatch, Digital health
Esquema
| ☆ | Tweet: Wearable ECG devices in patients with congenital long QT syndrome (LQTS): a French multicenter study (SMART-QT study). |
Vol 117 - N° 5
P. 313-320 - mai 2024 Regresar al número
Artículo precedente
- Atrioventricular conduction disorders in aortic valve infective endocarditis
- Mary Philip, Jérôme Hourdain, Noémie Resseguier, Frédérique Gouriet, Jean-Paul Casalta, Florent Arregle, Sandrine Hubert, Alberto Riberi, Jean-Philippe Mouret, Vartan Mardigyan, Jean-Claude Deharo, Gilbert Habib
- Aortic valve replacement for aortic stenosis: Influence of centre volume on TAVR adoption rates and outcomes in France
- Nadav Willner, Virginia Nguyen, Graeme Prosperi-Porta, Helene Eltchaninoff, Ian G. Burwash, Morgane Michel, Eric Durand, Martine Gilard, Christel Dindorf, Julien Dreyfus, Bernard Iung, Alain Cribier, Alec Vahanian, Karine Chevreul, David Messika-Zeitoun
Bienvenido a EM-consulte, la referencia de los profesionales de la salud.