Frailty index and its relation to falls and overnight hospitalizations in elderly Chinese people: A population-based study - 06/12/24

Doi : 10.1007/s12603-015-0625-6 
Z. Liu 1, *, Q. Wang 2, *, T. Zhi 3, 4, *, Y. Zhu 5, Y. Wang 5, Z. Wang 5, J. Shi 5, X. Xie 5, X. Chu 5, X. Wang 1, Xiaoyan Jiang 3, 4
1 Unit of epidemiology, State Key Laboratory of Genetic Engineering and MOE Key Laboratory of Contemporary Anthropology, School of Life Sciences and Institutes of Biomedical Sciences, Fudan University, 200433, Shanghai, China 
2 Department of Cardiology, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, 200092, Shanghai, China 
3 Key Laboratory of Arrhythmias of the Ministry of Education of China, Tongji University School of Medicine, 200092, Shanghai, China 
4 Department of Pathology and Pathophysiology, Tongji University School of Medicine, 200092, Shanghai, China 
5 Rugao People's Hospital, 226500, Rugao, Jiangsu, China 

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Abstract

Objectives

To investigate current status of frailty index (FI) defined as deficit accumulation and its relations to falls and overnight hospitalizations in an elderly Chinese population.

Design

A cross-sectional cohort study.

Setting

All of the 31 valiages in Jiang'an township, a typical medium-sized township in Rugao city, China.

Participants

Overall 1773 participants aged 70-84 years were randomly recruited.

Measurements

A FI including symptoms, activities of daily living, co-morbidities, cognitive and psychological function was constructed using 45 health deficits.

Results

The mean of FI was 0.14 in men and 0.19 in women. According to a usual FI cut-point of 0.25, 8.2% of men and 23.2% of women were classified as frail. Literate participants had lower levels of FI than their illiterate counterpart. In men, the FI was positively related to age (r = 0.186, p<.001), with a mean rate of deficit accumulation of 0.032 (on a log scale) per year. Each increment of 0.01 on the FI was associated with significantly increased risks of falls and overnight hospitalizations, with odds ratios of 1.05 (95% CI: 1.03, 1.07) and 1.05 (95% CI: 1.03, 1.08). Similarly, the aforementioned associations were observed in women. Education level moderated the associations of FI with falls in men and women.

Conclusion

Elderly Chinese women were more frail than men. The FI significantly increased with chronological age and was significantly associated with falls and overnight hospitalizations, and education level may play an important role. This study provides preliminary but crucial evidences for future researches on frailty in China.

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Key words : Frailty index, fall, overnight hospitalization, elderly


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Vol 20 - N° 5

P. 561-566 - mai 2016 Regresar al número
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