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Identifying high-risk central lines in critically ill children: A novel nurse-driven screening and mitigation intervention to reduce CLABSI - 24/02/25

Doi : 10.1016/j.ajic.2024.10.029 
Stephanie Morgenstern, MSN, APRN, ACCNS-P a, , Katie Thompson, DNP, APRN, ACCNS-P a, Stephanie Panton, MSN, RN a, Vivian Donnelly, CIC b, Sara Pau, MHS, CIC b, Kat Nelson, BSN, RN a, Lauren Booth, CRNP, MSN c, Taylor McIlquham, MPH, CIC b, Jessica Kitlas, BSN, RN a, Christina Schumacher, PhD, MHS d, Aaron M. Milstone, MD, MHS b, d, e, Meghan Bernier, MD c, d, Anna C. Sick-Samuels, MD, MPH b, d, e
a Department of Pediatric Nursing, Johns Hopkins Hospital, Baltimore, MD 
b Department of Hospital Epidemiology and Infection Control, Johns Hopkins Hospital, Baltimore, MD 
c Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 
d Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD 
e Armstrong Institute of Patient Safety and Quality, Johns Hopkins University School of Medicine, Baltimore, MD 

Address correspondence to Stephanie Morgenstern, MSN, APRN, ACCNS-P, Johns Hopkins Children’s Center, 1800 Orleans St, Bloomberg 4N, Baltimore, MD 21287.Johns Hopkins Children’s Center1800 Orleans St, Bloomberg 4NBaltimoreMD21287

Resumen

Background

Despite strong adherence to central line-associated bloodstream infection (CLABSI) infection prevention bundles, the CLABSI rate in our academic pediatric intensive care unit (PICU) and pediatric cardiac intensive unit (PCICU) remained high.

Methods

We developed a novel screening tool that stratified patients' risk for CLABSI and considered risk mitigation strategies.

Results

Of 1,583 screenings, 30% were classified as high-risk, 27% as moderate-risk, and 43% as low-risk. With accurate screening, the tool was 100% sensitive to patients who developed CLABSI, with a negative predictive value of 100% for low-risk screens. The CLABSI rate declined from 1.83 per 1,000 catheter-days to 0.98 and 1.02 in 2021 and 2022, respectively, with unprecedented consecutive months CLABSI-free. Device utilization was stable across both units, declining by 19% in the PICU and rising in the PCICU with increased cardiac surgeries. Clinicians expressed increased awareness of patient CLABSI risk factors and mitigation strategies in surveys.

Discussion

This novel screening tool effectively identified high-risk patients to target resources and promoted improvements in CLABSI prevention processes in the PICU and PCICU.

Conclusions

A novel nurse-driven CLABSI risk factor screening tool identified and focused resources on patients at high-risk for CLABSI, and increased awareness and proactive risk mitigation by clinicians.

El texto completo de este artículo está disponible en PDF.

Highlights

Central line--associated bloodstream infections (CLABSI) remain challenging.
We developed a nurse-led CLABSI risk screening tool.
A new screening approach helped risk stratify and target CLABSI mitigation efforts.

El texto completo de este artículo está disponible en PDF.

Key Words : Central line, Pediatric, PICU, Pediatric intensive care, Risk factors, Infection


Esquema


 Funding/support: This work was funded in part by the NIH grant K23HL161449 to Dr Sick-Samuels and grant K24AI141580 to Dr Milstone. The content is solely the responsibility of the authors and does not necessarily represent the official views of the funding agencies.
 Conflicts of interest: None to report.


© 2024  Association for Professionals in Infection Control and Epidemiology, Inc.. Publicado por Elsevier Masson SAS. Todos los derechos reservados.
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Vol 53 - N° 3

P. 381-386 - mars 2025 Regresar al número
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