Neonatal Hypoglycemia - 19/05/25

Doi : 10.1016/j.pcl.2025.04.002

Rakhi Gupta Basuray, MD ^a,^b,^⁎ , Alana Painter, MD ^a,^b, Shimona B. Thakrar, DO, MPH ^c,^d, Kathryn Westphal, MD ^a,^b
^a Department of Pediatrics, College of Medicine, The Ohio State University
^b Division of Pediatric Hospital Medicine, Nationwide Children’s Hospital, Columbus, OH, USA
^c Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA
^d Division of Pediatric Hospital Medicine, Texas Children's Hospital North Austin Campus, 9835 North Lake Creek Parkway, Austin, TX 78717, USA

^∗Corresponding author. 611 East Livingston Avenue, Columbus, OH 43205.611 East Livingston AvenueColumbusOH43205

En prensa. Pruebas corregidas por el autor. Disponible en línea desde el Monday 19 May 2025
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Resumen

Neonatal hypoglycemia is a common condition. Consensus on significant values has been difficult to establish. Due to potential for long-term impacts, screening and treatment are recommended. Infants at risk warrant monitoring. Various modalities exist to measure glucose levels. Plasma concentrations remain most accurate. Acute symptoms overlap with other conditions and are best treated with intravenous dextrose fluids. Asymptomatic newborns can be supported with enteral options that minimize separation of the mother-infant dyad. Further research into physiologic neonatal glycemic trends and the relation to long-term outcomes could aid in the prevention of overdiagnosis and overtreatment while providing reassurance against harm.

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Keywords : Neonatal hypoglycemia, Glucose homeostasis, Dextrose