Left Ventricular Non-Compaction Associated with a Genetic Variant of the CYP2C9 Gene - 16/08/11
, Hanns-Georg Klein, MD b, Olaf Elert, MD, PhD a
Corresponding author. Tel.: +49 931 201 33001; fax: +49 931 201 33009.Resumen |
Polymorphisms in the CYP2C9 gene can have a significant impact on drug therapy by affecting the pharmacokinetics of frequently prescribed drugs, such as phenprocoumon and warfarin. It is essential therefore that genetic CYP2C9 variants are excluded in patients with a suspected intolerance of anticoagulant therapy. Here we present the first report of a case of left ventricular non-compaction syndrome associated with a genetic variant of the CYP2C9 gene in a 45-year-old woman with myocardial insufficiency who was scheduled for implantation of a cardioverter defibrillator.
El texto completo de este artículo está disponible en PDF.Keywords : Left ventricular non-compaction, CYP2C9 genotype
Esquema
Vol 15 - N° 4
P. 269-271 - août 2006 Regresar al número
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