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GERIATRIC NEUROLOGY - 08/09/11

Doi : 10.1016/S0733-8619(05)70080-3 
Germaine L. Odenheimer, MD *

Resumen

Clinical neurology is evolving in response to major changes in demography and prevalence rates of diseases associated with advanced age. Neurologic conditions, especially dementia and stroke, are leading causes of disability and institutionalization in the elderly. These and other common age-associated conditions are readily identified in current clinical practice. But as our patients age, numerous issues become evident that do not lend themselves readily to traditional models of practice in neurology. Whereas the fields of geriatric medicine and geriatric psychiatry have been formally recognized, the development of geriatric neurology has lagged behind. And yet, neurologic disorders account for about half of those patients older than 65 who are incapacitated and for more than 90% of those whose incapacities are severe.1, 12

The aging nervous system offers challenges in terms of placing disease and treatment in the context of predicted aging changes in neurochemistry, neurohistology, neuroanatomy, neurophysiology, and neuroimmunology. Treatments must be selected based on understanding aging changes in absorption, lean/fat body tissue ratios, hepatic metabolism, and renal clearance, as well as the interactions of multiple diseases and medications. In addition, consideration must be given to the behavioral consequences, functional demands, and social setting of the individual.

The concept of looking for one disease to explain a constellation of signs and symptoms is not particularly useful in older patients. A patient older than 65 is likely to take more than three medications and have at least as many medical diagnoses of significance.9 They are a highly heterogeneous population who are likely to differ dramatically from one another in fitness levels and pathologies. Their presenting complaints tend to be quite atypical from what we have learned to expect of specific disorders. In fact, the elderly often present with “nonfocal” neurologic dysfunctions such as confusion, urinary incontinence, insomnia, and gait disturbances and falls as the earliest indicators for many nonneurologic disorders including myocardial infarction, pulmonary embolism, urinary tract infection, pneumonia, or fecal impaction.

The functional abilities, competency, and social support systems of the patient dictate the interventions more than diagnoses or age per se. This article lays the conceptual ground work for the fundamental issues inherent to geriatric neurology that require special attention in training our residents, practitioners, and specialists.

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 Address reprint requests to Germaine L. Odenheimer, MD, South Carolina Department of Mental Health, William S. Hall Psychiatric Institute, 1800 Colonial Drive (Box 202), Columbia, SC 29202, glo67@infoave.net


© 1998  W. B. Saunders Company. Publicado por Elsevier Masson SAS. Todos los derechos reservados.
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Vol 16 - N° 3

P. 561-567 - août 1998 Regresar al número
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  • THE AGING POPULATION : Implications for the Burden of Neurologic Disease
  • Jack E. Riggs
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  • NEUROPATHOLOGY OF AGING
  • Sydney S. Schochet

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