Arthritis Pathology - 08/02/12

Doi : 10.1016/j.path.2011.07.009

Edward F. DiCarlo, MD ^a,^b, Michael J. Klein, MD ^a,^b,^c,^⁎
^a Department of Pathology and Laboratory Medicine, Hospital for Special Surgery, 535 East 70th Street, New York, NY 10021, USA
^b Joan and Sanford Weill College of Medicine of Cornell University, 1300 York Avenue, New York, NY 10065, USA
^c Memorial Sloan-Kettering Cancer Center and Memorial Hospital for Cancer and Allied Diseases, 1275 York Avenue, New York, NY 10065, USA

Corresponding author. Department of Pathology and Laboratory Medicine, Hospital for Special Surgery, 535 East 70th Street, New York, NY 10021.

Abstract

The pathologic examination of failed joints, whether natural or artificial, is an indispensable part of the understanding of arthritis, as it is the last, and still best opportunity to determine or verify the correct diagnosis. Accuracy in pathologic diagnosis, based on a firm understanding of the various disease processes, provides reliable data for use in clinical registries, provides an opportunity to explain the “unusual” clinical presentation, and ultimately gives the “best evidence” for basing further treatments and prognosis for the individual patient.

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Keywords : Degenerative joint disease, Osteoarthritis, Subchondral insufficiency fracture, Inflammatory disease, Avascular necrosis, Septic/infectious arthritis, Joint replacement, Gout, Iron overload, Ochronosis