Autoinflammatory Syndromes - 03/07/13
Resumen |
Autoinflammatory syndromes comprise a diagnostically challenging group of systemic inflammatory disorders uniquely related by (1) dysregulation of innate immunity, (2) inflammasome activation, (3) dramatic clinical features (high fevers, neutrophilic rashes, and bone or synovial involvement), (4) impressive acute phase responses, and (5) effective treatment with cytokine inhibitors. This review details some of the more common autoinflammatory disorders, their distinguishing features and dermatologic manifestations, and how an accurate diagnosis can be established in patients presenting with periodic or intermittent febrile disorders.
El texto completo de este artículo está disponible en PDF.Keywords : Autoinflammatory, CAPS, Periodic fever, Still disease
Esquema
| Disclosures: Clinical investigator for Genentech, Pfizer, UCB, Celgene, Novartis, Amgen, NIH, and CORRONA; advisor and consultant to Janssen, Abbott, UCB, Pfizer, BMS, Amgen, Genentech, Savient, and Celgene. Dr Cush holds no stock or investments in these companies and does not partake in industry “speaker’s bureaus” or give industry-guided “promotional lectures.” |
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| Funded by: NIH U19 082715. |
Vol 31 - N° 3
P. 471-480 - juillet 2013 Regresar al númeroBienvenido a EM-consulte, la referencia de los profesionales de la salud.
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