Correlation between imaging and molecular classification of breast cancers - 09/11/13

Doi : 10.1016/j.diii.2013.04.010

M. Boisserie-Lacroix ^a,^⁎ , G. Hurtevent-Labrot ^a, S. Ferron ^a, N. Lippa ^a, H. Bonnefoi ^b,^c, G. Mac Grogan ^d
^a Breast Imaging Unit, Department of Medical Imaging, Institut Bergonié, 229, cours de l’Argonne, 33076 Bordeaux cedex, France
^b Department of Medical Oncology, Institut Bergonié, 229, cours de l’Argonne, 33076 Bordeaux cedex, France
^c Université Bordeaux, INSERM U916, 33000 Bordeaux, France
^d Department of Anatomic Pathology, Institut Bergonié, 229, cours de l’Argonne, 33076 Bordeaux cedex, France

^⁎Corresponding author.

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Abstract

The histological type of tumour according to the WHO: ductal, lobular, rare forms, is correlated with specific aspects of the imaging based on each type. This morphological classification was improved by knowledge of the molecular anomalies of breast cancers, resulting in the definition of cancer sub-groups with distinct prognoses and different responses to treatment: luminal A, luminal B, HER2 positive, basal-like, triple-negative. Studies are beginning to deal with the appearance of each sub-type in the imaging. It is now important for the radiologist to be familiar with them.

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Keywords : Breast cancer, Mammography, Sonography, MRI, Molecular classification