Arterial spin labeling (ASL) perfusion: Techniques and clinical use - 02/12/13

Doi : 10.1016/j.diii.2013.06.010

J.-C. Ferré ^a,^b,^c,^d,^⁎ , E. Bannier ^b,^c,^d, H. Raoult ^a,^b,^c,^d, G. Mineur ^a, B. Carsin-Nicol ^a, J.-Y. Gauvrit ^a,^b,^c,^d
^a CHU de Rennes, Department of Radiology, Hôpital Pontchaillou, 2, rue Henri-Le-Guilloux, 35033 Rennes cedex 9, France
^b Plateforme Neurinfo, CHU de Rennes, Hôpital Pontchaillou, 2, rue Henri-Le-Guilloux, 35033 Rennes cedex 9, France
^c INRIA, VisAGeS unité/projet U746, 35042 Rennes, France
^d INSERM VisAGeS unité/projet U746, UMR 6074, Irisa, Université Rennes 1, 35043 Rennes cedex, France

^⁎Corresponding author. CHU de Rennes, Department of Radiology, Hôpital Pontchaillou, 2, rue Henri-Le-Guilloux, 35033 Rennes cedex 9, France.

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Abstract

Arterial spin labeling (ASL) perfusion is a MRI technique to quantify tissue blood flow. ASL is a non-invasive technique that labels the protons in the arterial blood by radiofrequency pulses, without the exogenous injection of contrast media. This article has three goals: 1) present the principles of ASL perfusion, the types of labeling and the ways to obtain the mapping; 2) specify and the quality criteria for the mapping obtained, while emphasizing the artifacts; and 3) describe the main encephalic and renal applications.

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Keywords : MRI, Perfusion, Brain, Kidney