Executive function processes mediate the impact of working memory impairment on intelligence in schizophrenia - 15/01/15
, V. Kumari a, b, R.G. Morris aBienvenido a EM-consulte, la referencia de los profesionales de la salud.
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Abstract |
Objective |
The study investigated working memory, executive functions (conceptualized as response inhibition, updating, and shifting), and intelligence in schizophrenia, using structural equation modelling to determine the relationship between working memory and intelligence, testing whether specific executive functions act as a mediator for the association.
Method |
One hundred and twenty-five individuals diagnosed with schizophrenia and 64 healthy participants were included in the study, tested using measures of working memory, intelligence and executive functioning. Structural equation modelling (SEM) was used to estimate direct and indirect associations between main measures.
Results |
The schizophrenia group had significantly lower working memory, executive function and intelligence than the healthy group. The relationship between working memory and intelligence was significantly mediated by inhibition, updating and shifting functions.
Conclusion |
The study indicates a mediating role of executive functions in determining the association between working memory and intellectual function in schizophrenia. It is further proposed that in people with schizophrenia, cognitive remediation approaches targeting working memory through executive functioning may in turn improve intellectual function generally.
El texto completo de este artículo está disponible en PDF.Keywords : Working memory, Executive functions, Intelligence, Schizophrenia, Structural equation modelling
Esquema
Vol 30 - N° 1
P. 1-7 - janvier 2015 Regresar al número
- Cognition and autonomic function in schizophrenia: Inferior cognitive test performance in electrodermal and niacin skin flush non-responders
- B.M. Nilsson, G. Holm, C.M. Hultman, L. Ekselius
Bienvenido a EM-consulte, la referencia de los profesionales de la salud.
El acceso al texto completo de este artículo requiere una suscripción.
Bienvenido a EM-consulte, la referencia de los profesionales de la salud.
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