Adrenal Mild Hypercortisolism - 31/05/15

Doi : 10.1016/j.ecl.2015.02.009

Gillian M. Goddard, MD ^a,^b, Aarti Ravikumar, MD ^a, Alice C. Levine, MD ^a,^⁎
^a The Hilda and J. Lester Gabrilove Division of Endocrinology, Diabetes and Bone Diseases, Department of Internal Medicine, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, Box 1055, New York, NY 10029-6574, USA
^b Lennox Hill Hospital, North Shore-LIJ Health System, New York, NY 10075, USA

^∗Corresponding author.

Resumen

Adrenal incidentalomas have become detected more often as the use of abdominal imaging has increased. Up to one-third of these may be secreting low levels of cortisol, known as mild hypercortisolism or subclinical Cushing syndrome. These low levels of cortisol have been found to be associated with an increased in the metabolic syndrome, osteoporosis, cardiovascular events, and mortality. This article discusses in detail the epidemiology, diagnosis, clinical associations, and treatment options of mild hypercortisolism.

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Keywords : Adrenal, Adrenal incidentaloma, Mild hypercortisolism, Subclinical Cushing syndrome, Cushing syndrome, Cortisol