Índice

• • ·Cover 1

    Página :OFC

    
• • ·Brief Overview of This Month's JACI

    Página :5A

    
• • ·Table of Contents

    Página :9A

    
• • ·Editorial Board

    Página :29A

    

• Reader services

  • ·Information for Readers

    Página :30A

    
  • ·News & Notes

    Página :32A

    Esquema Esquema
  • ·CME Activities Calendar

    Página :38A

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• News beyond our pages

  • ·News Beyond Our Pages

    Página :1137-1138

    Marc E. Rothenberg, Jean Bousquet

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• Reviews and feature articles

  • ·Genetic errors of the human caspase recruitment domain–B-cell lymphoma 10–mucosa-associated lymphoid tissue lymphoma-translocation gene 1 (CBM) complex: Molecular, immunologic, and clinical heterogeneity

    Página :1139-1149

    Rebeca Pérez de Diego, Silvia Sánchez-Ramón, Eduardo López-Collazo, Rubén Martínez-Barricarte, Carolina Cubillos-Zapata, Antonio Ferreira Cerdán, Jean-Laurent Casanova, Anne Puel

    Resumen Resumen Esquema Esquema  
  • ·Insights into primary immune deficiency from quantitative microscopy

    Página :1150-1162

    Emily M. Mace, Jordan S. Orange

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  • ·Potential role of reduced environmental UV exposure as a driver of the current epidemic of atopic dermatitis

    Página :1163-1169

    Jacob P. Thyssen, Matthew J. Zirwas, Peter M. Elias

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  • ·Nocturnal eczema: Review of sleep and circadian rhythms in children with atopic dermatitis and future research directions

    Página :1170-1177

    Anna B. Fishbein, Olivia Vitaterna, Isabel M. Haugh, Aakash A. Bavishi, Phyllis C. Zee, Fred W. Turek, Stephen H. Sheldon, Jonathan I. Silverberg, Amy S. Paller

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  • ·Radiation-sensitive severe combined immunodeficiency: The arguments for and against conditioning before hematopoietic cell transplantation—what to do?

    Página :1178-1185

    Morton J. Cowan, Andrew R. Gennery

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  • ·Practice parameter for the diagnosis and management of primary immunodeficiency

    Página :1186

    Francisco A. Bonilla, David A. Khan, Zuhair K. Ballas, Javier Chinen, Michael M. Frank, Joyce T. Hsu, Michael Keller, Lisa J. Kobrynski, Hirsh D. Komarow, Bruce Mazer, Robert P. Nelson, Jordan S. Orange, John M. Routes, William T. Shearer, Ricardo U. Sorensen, James W. Verbsky, David I. Bernstein, Joann Blessing-Moore, David Lang, Richard A. Nicklas, John Oppenheimer, Jay M. Portnoy, Christopher R. Randolph, Diane Schuller, Sheldon L. Spector, Stephen Tilles, Dana Wallace, Francisco A. Bonilla, David A. Khan, David I. Bernstein, Joann Blessing-Moore, David Khan, David Lang, Richard A. Nicklas, John Oppenheimer, Jay M. Portnoy, Christopher R. Randolph, Diane Schuller, Sheldon L. Spector, Stephen Tilles, Dana Wallace, Francisco A. Bonilla, Zuhair K. Ballas, Javier Chinen, Michael M. Frank, Joyce T. Hsu, Michael Keller, Lisa J. Kobrynski, Hirsh D. Komarow, Bruce Mazer, Robert P. Nelson, Jordan S. Orange, John M. Routes, William T. Shearer, Ricardo U. Sorensen, James W. Verbsky

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• The Editors' choice

  • ·The Editors' Choice

    Página :1206-1207

    Donald Y.M. Leung, Stanley J. Szefler, Associate Editors of the JACI

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• Asthma and lower airway disease

  • ·Duration of wheezy episodes in early childhood is independent of the microbial trigger

    Página :1208

    Christian J. Carlsson, Nadja H. Vissing, Astrid Sevelsted, Sebastian L. Johnston, Klaus Bønnelykke, Hans Bisgaard

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  • ·Effect of pregnancy in asthma on health care use and perinatal outcomes

    Página :1215

    Sujeong Kim, Jinhee Kim, So Young Park, Hye-Yeon Um, Kyoungjoo Kim, Yuri Kim, Yunjin Park, Seunghee Baek, Sun-Young Yoon, Hyouk-Soo Kwon, You Sook Cho, Hee-Bom Moon, Tae-Bum Kim

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  • ·Patterns of IgE responses to multiple allergen components and clinical symptoms at age 11 years

    Página :1224-1231

    Angela Simpson, Nevena Lazic, Danielle C.M. Belgrave, Phil Johnson, Christopher Bishop, Clare Mills, Adnan Custovic

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  • ·Prostaglandin E₂ inhibits mast cell–dependent bronchoconstriction in human small airways through the E prostanoid subtype 2 receptor

    Página :1232

    Jesper Säfholm, Martijn L. Manson, Johan Bood, Ingrid Delin, Ann-Charlotte Orre, Per Bergman, Mamdoh Al-Ameri, Sven-Erik Dahlén, Mikael Adner

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  • ·Genetic risk factors for decreased bone mineral accretion in children with asthma receiving multiple oral corticosteroid bursts

    Página :1240

    Heung-Woo Park, Bing Ge, Szeman Tse, Elin Grundberg, Tomi Pastinen, H. William Kelly, Kelan G. Tantisira

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• Rhinitis, sinusitis, and upper airway disease

  • ·Fish and polyunsaturated fat intake and development of allergic and nonallergic rhinitis

    Página :1247

    Jessica Magnusson, Inger Kull, Marit Westman, Niclas Håkansson, Alicja Wolk, Erik Melén, Magnus Wickman, Anna Bergström

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• Atopic dermatitis and skin disease

  • ·The Asian atopic dermatitis phenotype combines features of atopic dermatitis and psoriasis with increased T_H17 polarization

    Página :1254-1264

    Shinji Noda, Mayte Suárez-Fariñas, Benjamin Ungar, Soo Jung Kim, Cristina de Guzman Strong, Hui Xu, Xiangyu Peng, Yeriel D. Estrada, Saeko Nakajima, Tetsuya Honda, Jung U. Shin, Hemin Lee, James G. Krueger, Kwang-Hoon Lee, Kenji Kabashima, Emma Guttman-Yassky

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  • ·Severe dermatitis, multiple allergies, and metabolic wasting syndrome caused by a novel mutation in the N-terminal plakin domain of desmoplakin

    Página :1268-1276

    Maeve A. McAleer, Elizabeth Pohler, Frances J.D. Smith, Neil J. Wilson, Christian Cole, Stuart MacGowan, Jennifer L. Koetsier, Lisa M. Godsel, Robert M. Harmon, Robert Gruber, Debra Crumrine, Peter M. Elias, Michael McDermott, Karina Butler, Annemarie Broderick, Ofer Sarig, Eli Sprecher, Kathleen J. Green, W.H. Irwin McLean, Alan D. Irvine

    Resumen Resumen Esquema Esquema  
  • ·Alopecia areata profiling shows T_H1, T_H2, and IL-23 cytokine activation without parallel T_H17/T_H22 skewing

    Página :1277-1287

    Mayte Suárez-Fariñas, Benjamin Ungar, Shinji Noda, Anjali Shroff, Yasaman Mansouri, Judilyn Fuentes-Duculan, Annette Czernik, Xiuzhong Zheng, Yeriel D. Estrada, Hui Xu, Xiangyu Peng, Avner Shemer, James G. Krueger, Mark G. Lebwohl, Emma Guttman-Yassky

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  • ·Atopic dermatitis: Age and race do matter!

    Página :1265-1267

    Donald Y.M. Leung

     

• Food, drug, insect sting allergy, and anaphylaxis

  • ·Peripheral blood eosinophilia and hypersensitivity reactions among patients receiving outpatient parenteral antibiotics

    Página :1288

    Kimberly G. Blumenthal, Ilan Youngster, Dustin J. Rabideau, Robert A. Parker, Karen S. Manning, Rochelle P. Walensky, Sandra B. Nelson

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  • ·Peanut defensins: Novel allergens isolated from lipophilic peanut extract

    Página :1295

    Arnd Petersen, Skadi Kull, Sandra Rennert, Wolf-Meinhard Becker, Susanne Krause, Martin Ernst, Thomas Gutsmann, Johann Bauer, Buko Lindner, Uta Jappe

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  • ·Breast-feeding does not protect against allergic sensitization in early childhood and allergy-associated disease at age 7 years

    Página :1302

    Ea Jelding-Dannemand, Ann-Marie Malby Schoos, Hans Bisgaard

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  • ·Association between vitamin D levels and allergy-related outcomes vary by race and other factors

    Página :1309

    Ganesa Wegienka, Suzanne Havstad, Edward M. Zoratti, Haejin Kim, Dennis R. Ownby, Christine Cole Johnson

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• Immune deficiencies, infection, and systemic immune disorders

  • ·TNF receptor superfamily member 13b (TNFRSF13B) hemizygosity reveals transmembrane activator and CAML interactor haploinsufficiency at later stages of B-cell development

    Página :1315-1325

    Neil Romberg, Manmeet Virdee, Nicolas Chamberlain, Tyler Oe, Jean-Nicolas Schickel, Tiffany Perkins, Tineke Cantaert, Rima Rachid, Sally Rosengren, Regina Palazzo, Raif Geha, Charlotte Cunningham-Rundles, Eric Meffre

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  • ·Single-cell systems-level analysis of human Toll-like receptor activation defines a chemokine signature in patients with systemic lupus erythematosus

    Página :1326-1336

    William E. O'Gorman, Elena W.Y. Hsieh, Erica S. Savig, Pier Federico Gherardini, Joseph D. Hernandez, Leo Hansmann, Imelda M. Balboni, Paul J. Utz, Sean C. Bendall, Wendy J. Fantl, David B. Lewis, Garry P. Nolan, Mark M. Davis

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  • ·Single amino acid charge switch defines clinically distinct proline-serine-threonine phosphatase-interacting protein 1 (PSTPIP1)–associated inflammatory diseases

    Página :1337-1345

    Dirk Holzinger, Selina Kathleen Fassl, Wilco de Jager, Peter Lohse, Ute F. Röhrig, Marco Gattorno, Alessia Omenetti, Sabrina Chiesa, Francesca Schena, Judith Austermann, Thomas Vogl, Douglas B. Kuhns, Steven M. Holland, Carlos Rodríguez-Gallego, Ricardo López-Almaraz, Juan I. Arostegui, Elena Colino, Rosa Roldan, Smaragdi Fessatou, Bertrand Isidor, Sylvaine Poignant, Koichi Ito, Hans-Joerg Epple, Jonathan A. Bernstein, Michael Jeng, Jennifer Frankovich, Geraldina Lionetti, Joseph A. Church, Peck Y. Ong, Mona LaPlant, Mario Abinun, Rod Skinner, Venetia Bigley, Ulrich J. Sachs, Claas Hinze, Esther Hoppenreijs, Jan Ehrchen, Dirk Foell, Jae Jin Chae, Amanda Ombrello, Ivona Aksentijevich, Cord Sunderkoetter, Johannes Roth

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• Mechanisms of allergy and clinical immunology

  • ·Respiratory syncytial virus infection of primary human mast cells induces the selective production of type I interferons, CXCL10, and CCL4

    Página :1346

    Ayham Al-Afif, Raidan Alyazidi, Sharon A. Oldford, Yan Y. Huang, Christine A. King, Nico Marr, Ian D. Haidl, Robert Anderson, Jean S. Marshall

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  • ·Dectin-1 activation unlocks IL12A expression and reveals the T_H1 potency of neonatal dendritic cells

    Página :1355

    Sébastien Lemoine, Barbara Jaron, Sabrine Tabka, Chourouk Ettreiki, Edith Deriaud, Dania Zhivaki, Camille Le Ray, Odile Launay, Laleh Majlessi, Pierre Tissieres, Claude Leclerc, Richard Lo-Man

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  • ·Analysis of glutathione S-transferase allergen cross-reactivity in a North American population: Relevance for molecular diagnosis

    Página :1369-1377

    Geoffrey A. Mueller, Lars C. Pedersen, Jill Glesner, Lori L. Edwards, Josefina Zakzuk, Robert E. London, L. Karla Arruda, Martin D. Chapman, Luis Caraballo, Anna Pomés

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  • ·Human seroreactivity to gut microbiota antigens

    Página :1378

    Benjamin S. Christmann, Thomas R. Abrahamsson, Charles N. Bernstein, L. Wayne Duck, Peter J. Mannon, Göran Berg, Bengt Björkstén, Maria C. Jenmalm, Charles O. Elson

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  • ·Skin dendritic cells induce follicular helper T cells and protective humoral immune responses

    Página :1387

    Chen Yao, Sandra M. Zurawski, Elizabeth S. Jarrett, Brian Chicoine, Juliet Crabtree, Erik J. Peterson, Gerard Zurawski, Daniel H. Kaplan, Botond Z. Igyártó

    Resumen Resumen Esquema Esquema  

• Letters to the Editor

  • ·Mode of delivery—impact on risk of noncommunicable diseases

    Página :1398-1399

    Reetta Miettinen, Henriina Hermansson, Marko Merikukka, Mika Gissler, Erika Isolauri

    
  • ·Impaired efferocytosis in human chronic granulomatous disease is reversed by pioglitazone treatment

    Página :1399

    Ruby F. Fernandez-Boyanapalli, Emilia Liana Falcone, Christa S. Zerbe, Beatriz E. Marciano, S. Courtney Frasch, Peter M. Henson, Steven M. Holland, Donna L. Bratton

     
  • ·Broad spectrum of autoantibodies in patients with Wiskott-Aldrich syndrome and X-linked thrombocytopenia

    Página :1401

    Elena Crestani, Stefano Volpi, Fabio Candotti, Silvia Giliani, Lucia Dora Notarangelo, Julia Chu, Juan Carlos Aldave Becerra, David Buchbinder, Janet Chou, Raif S. Geha, Maria Kanariou, Alejandra King, Cinzia Mazza, Daniele Moratto, Robert Sokolic, Elizabeth Garabedian, Fulvio Porta, Maria Caterina Putti, Rima H. Wakim, Erdyni Tsitsikov, Sung-Yun Pai, Luigi D. Notarangelo

     
  • ·Impaired microbial killing by neutrophils from patients with protein kinase C delta deficiency

    Página :1404

    Katka Szilagyi, Roel P. Gazendam, John L. van Hamme, Anton T.J. Tool, Michel van Houdt, Wilhelm A.J.W. Vos, Paul Verkuijlen, Hans Janssen, Alexandre Belot, Laurent Juillard, Elisabeth Förster-Waldl, Kaan Boztug, Georg Kraal, Menno P.J. de Winther, Taco W. Kuijpers, Timo K. van den Berg

     
  • ·Continuing IgG replacement therapy for hypogammaglobulinemia after rituximab—for how long?

    Página :1407-1409

    Sara Barmettler, Christina Price

    
  • ·Measuring the effect of asthma control on exacerbations and health resource use

    Página :1409

    Patrick W. Sullivan, Jonathan D. Campbell, Gary Globe, Vahram H. Ghushchyan, Bruce Bender, Michael Schatz, Yun Chon, J. Michael Woolley, David J. Magid

     
  • ·Endemic mycoses in patients with STAT3-mutated hyper-IgE (Job) syndrome

    Página :1411

    Camila D. Odio, Ki Lee Milligan, Katherine McGowan, Amanda K. Rudman Spergel, Rachel Bishop, Lisa Boris, Amanda Urban, Pamela Welch, Theo Heller, David Kleiner, Mary Anne Jackson, Steven M. Holland, Alexandra F. Freeman

     
  • ·CpG-DNA enhances the tight junction integrity of the bronchial epithelial cell barrier

    Página :1413

    Terufumi Kubo, Paulina Wawrzyniak, Hideaki Morita, Kazunari Sugita, Kerstin Wanke, Jeannette I. Kast, Can Altunbulakli, Beate Rückert, Bogdan Jakiela, Marek Sanak, Mübeccel Akdis, Cezmi A. Akdis

     
  • ·New wheat allergens related to baker's asthma

    Página :1416

    Cordula Bittner, Ulrike Peters, Karsten Frenzel, Horst Müsken, Reinhold Brettschneider

    
  • ·A neuropathological study of cerebrovascular abnormalities in a signal transducer and activator of transcription 3–deficient patient

    Página :1418

    Marie-Olivia Chandesris, Françoise Gray, Patrick Bruneval, Arshid Azarine, Nathalie Boddaert, Catherine Oppenheim, François Paraire, Emmanuel Touzé, Damien Bonnet, Olivier Hermine, Olivier Lortholary, Valérie Cormier-Daire, Pierre Boutouyrie, Ziad Mallat, Alain Fischer, Capucine Picard

     

• Correspondence

  • ·Recommendations on probiotics in allergy prevention should not be based on pooling data from different strains

    Página :1422

    Hania Szajewska, Raanan Shamir, Dominique Turck, Johannes B. van Goudoever, Walter A. Mihatsch, Mary Fewtrell

     
  • ·Reply

    Página :1423-1425

    Carlos A. Cuello-Garcia, Jan L. Bro?ek, Alessandro Fiocchi, Ruby Pawankar, Juan José Yepes-Nuñez, Luigi Terracciano, Shreyas Gandhi, Arnav Agarwal, Yuan Zhang, Holger J. Schünemann

     
  • ·Impact of sex on anaphylaxis severity—data from the Anaphylaxis Registry

    Página :1425-1426

    Wojciech Francuzik, Maria Nassiri, Magda Babina, Margitta Worm

    
  • ·Reply

    Página :1426

    Valerie Hox, Dean D. Metcalfe, Ana Olivera

    
  • ·Allergenic significance of cephalosporin side chains

    Página :1426-1428

    Brian A. Baldo, Nghia H. Pham

     
  • ·Reply

    Página :1428

    Antonino Romano, Francesco Gaeta, Rocco Luigi Valluzzi, Michela Maggioletti, Alessandra Zaffiro, Cristiano Caruso, Donato Quaratino