COVID-19-associated secondary sclerosing cholangitis – A case series of 4 patients - 24/11/22
, Margarida Mourato b, 1, Sofia Bragança a, Joana Batista Paulo b, Rita Sismeiro b, André Pereira c, Ana Nassauer Mónica d, Luís Carvalho Lourenço a, Mariana Cardoso a
Benvenuto su EM|consulte, il riferimento dei professionisti della salute.
Articolo gratuito.
Si connetta per beneficiarne
Abstract |
We report a case series of four patients diagnosed with COVID-19-associated secondary sclerosing cholangitis (SSC), a recently described rare late complication of severe COVID-19. Following prolonged stays in the intensive care unit, these patients developed marked sustained cholestasis and jaundice despite clinical improvement. Cholangiography showed beaded appearance of intra-hepatic bile ducts and bile casts were removed in one patient. None of the patients reached normalization of liver enzymes and at least one progressed to liver cirrhosis (follow-up time of 11 to 16 months). COVID-19-associated SSC has a dismal prognosis with rapid progression to advanced chronic liver disease.
Il testo completo di questo articolo è disponibile in PDF.Keywords : COVID-19, Secondary sclerosing cholangitis, Cholangiopathy, Case series
Abbreviations : (ALT), (ALP), (ANA), (AST), (cACLD), (CT), (COVID-19), (ERCP), (GGT), (H&E), (HBV), (ICU), (IMV), (MRCP), (PEEP), (SARS-CoV-2), (SSC), (SSC-CIP), (ULN)
Mappa
Vol 46 - N° 10
Articolo 102048- Dicembre 2022 Ritorno al numero
Articolo precedente
- Comprehensive analysis of treatment-related adverse events of immunotherapy in advanced gastric or gastroesophageal junction cancer: A meta-analysis of randomized controlled trials
- Hang Yuan, Dan-Dan Duan, Ya-Jun Zhang
- The risk of diabetes mellitus in patients with post-ERCP pancreatitis—A preliminary report
- Halim Francis, Perveen Aslam, Timothy Greenaway, Andrew Thomson
Benvenuto su EM|consulte, il riferimento dei professionisti della salute.