Neonatal Gabapentin Withdrawal Syndrome - 16/10/15
Abstract |
Introduction |
Gabapentin, an anticonvulsant, neuroleptic, and pain medication, is widely used in both adults and children for management of epilepsy, bipolar illness, and neuropathic pain. Gabapentin use has also been recommended for hyperemesis gravidarum and restless leg syndrome in pregnant mothers.
Objective |
Although gabapentin use is deemed safe during pregnancy, no clinical reports of gabapentin withdrawal syndrome in a neonate have been described.
Results |
We present a newborn who showed signs of withdrawal after prolonged in utero exposure to gabapentin.
Clinical Implications |
Clinicians should be aware of possible withdrawal symptoms from drugs such as gabapentin, administered to mothers during pregnancy. We also encourage the gradual tapering of gabapentin in neonates over weeks to months similar to the adult population.
Le texte complet de cet article est disponible en PDF.Keywords : gabapentin, withdrawal, newborn, pregnancy
Plan
| Funding Source: No funding was secured for this study. |
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| Financial Disclosure: Authors have no financial relationships relevant to this article to disclose. |
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| Conflict of Interest: Authors have no conflicts of interest to disclose. |
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| Clinical trial registration: Not applicable. |
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| Contributor's statement: Dr. Carrasco collected all data, interpreted the data, and wrote the first draft of the manuscript and approved the final manuscript as submitted; Dr. Rao critically reviewed and edited the manuscript and contributed references to the manuscript and approved the final manuscript as submitted; Dr. Bearer reviewed and edited the manuscript and approved the final manuscript as submitted; and Dr. Sundararajan conceptualized the case report, reviewed, and revised the manuscript and approved the final manuscript as submitted. |
Vol 53 - N° 5
P. 445-447 - novembre 2015 Retour au numéro
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