Statins and the Liver - 17/02/16
, Samira Bahrainy, MD b, Edward A. Gill, MD, FASE, FAHA, FACC, FACP, FNLA cRésumé |
Lipid lowering, particularly with 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors (“statins”), reduces the risk of cardiovascular disease. Patients with chronic liver disease present challenges to the use of lipid medications. In the case of most liver disorders, the concern has been one of safety. There is evidence that most lipid-lowering medications can be used safely in many situations, although large outcomes trials are lacking. This review examines lipid physiology and cardiovascular risk in specific liver diseases and reviews the evidence for lipid lowering and the use of statins in chronic liver disease.
Le texte complet de cet article est disponible en PDF.Keywords : Dyslipidemia, Chronic liver disease, Statins, Hepatic transaminases
Plan
| This article originally appeared in Cardiology Clinics, Volume 33, Issue 2, May 2015. |
Vol 45 - N° 1
P. 117-128 - mars 2016 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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