Risk associated to subtypes of seizure disorders in dementia patients - 13/04/16
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Résumé |
Introduction |
Seizure disorders have been identified in patients suffering from different types of dementia. However, the risks associated with the subtypes of those seizures have not been characterized.
Objective/aim |
To compare the occurrence of seizure disorders (partial and generalized) between patients with and without a dementia diagnosis from the OPTUM database.
Methods |
All ages, and patients with full eligibility between January of 2005 to December of 2014, were included. Data from OPTUM, a de-identified, HIPAA compliant database, made up of 40.7 million private insured patient individual electronic health records from the US, were utilized. Using ICD-9 diagnoses, the occurrence of generalized or partial seizure disorders was identified. A comparison between patients with and without dementia was performed.
Results |
A total of 150,516 patient records had a dementia diagnosis, and, 56.38% of them were females. Patients with dementia when compared to those without dementia had higher risk for seizure disorders [odds ratio (OR)=6.5 95% CI=4.4–9.5]; grand mal status (OR=6.5, 95% CI=5.7–7.3); partial seizures (OR=6.0, 95% CI=5.5–6.6); motor simple partial status (OR=5.6, 95% CI=3.5–9.0); epilepsy (OR=5.0, 95% CI=4.8–5.2); complex partial epileptic seizures (OR=4.9, 95% CI=4.6–5.2); generalized convulsive epilepsy (OR=4.8, 95% CI=4.5–5.0); localization-related epilepsy (OR=4.5, 95% CI=4.1–4.9); petit mal status (OR=4.2, 95% CI=2.9–6.1); fits convulsions (OR=3.5, 95% CI=3.4–3.6); and complex febrile seizure (OR=2.5, 95% CI=1.6–3.9).
Conclusions |
The present study confirms that patients with dementia have higher risks for either generalized or partial seizures disorders when compared with patients without dementia.
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Vol 33 - N° S
P. S138-S139 - mars 2016 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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