A case of marchiafava bignami disease with frontal cortex involvement and late onset, long-lasting psychiatric symptoms - 13/04/16
Résumé |
Aims |
To describe the case and management of a patient with marchiafava bignami disease (MBD) with frontal cortical lesions, no specific symptoms at first referral to the emergency room, and late onset of atypical psychiatric symptoms.
Methods |
We report the case of a 44-year-old patient with a history of chronic alcohol abuse, eventually diagnosed with MBD.
Results |
Magnetic resonance showed lesions in the splenium and in the body of corpus callosum and bilateral lesions of the frontal cortex. The patient showed late-onset atypical psychiatric symptoms, which were drug resistant.
Conclusions |
The case we describe seems to support the existing few ones describing cortical involvement in MBD, which suggest that this is associated with a poorer prognosis. Psychiatric symptoms may be challenging to treat because of drug resistance. The involvement of psychiatrists together with neurologists and radiologists, with a consultation–liaison approach has proved important for the achievement of diagnosis and of the most appropriate management and treatment for this patient.
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Vol 33 - N° S
P. S321 - mars 2016 Retour au numéro
Article précédent
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