High blood glucose (HBG) on admission is a major common metabolic disorder in patients with acute myocardial infarction (MI). However, only few data have examined its predictive performance over established risk score. The aim of our study was to determine if hyperglycemia on admission correlates to severity of coronary artery lesions evaluated by the Synthax score.

We evaluated 128 patients admitted for MI. The population was divided into: hyperglycemia (glycemia on admission >1.10g/l) and non-hyperglycemia (<1.10g/l) regardless of previous diabetic status.

63.4% of our patients presented with hyperglycemia on admission. Patients aged over 65 years old represented 89% of the population studied. There were significant differences in baseline clinical status established by calculating CHADSVASC score (2,60±1,54 vs 1,5±1,05; p=0.01). Biological status differed significantly between the two groups especially troponine Ic, LDL cholesterol and triglyceride which were higher in HBG patients (32,20±63,93 vs 17,64±31,16 p=0.014; 0,94± 0,33 vs 0,87±0,27 p=0.015; 1,45± 0,67 vs 1,16±,42 p=0.04 respectively). Synthax score was higher in the hyperglycemia group 11,21±8,377 vs 7,50±8,782 p=0.03. A multivariate linear regression analysis showed that hyperglycemia on admission was an independent predictor of severity of coronary artery lesions.

In patients with MI, hyperglycemia on admission predicts severity of coronary artery lesions so we should be more careful with this population.

The author hereby declares no conflict of interest