Unconventional side effects of antidepressants: Focus on emotional blunting - 08/07/17
Résumé |
Objectives |
The aim of this study was to investigate the unconventional side-effects of selective serotonin reuptake inhibitors (SSRIs) and tricyclics (TCAs) antidepressants during long-term treatment of depression, with a special focus on emotional blunting and, in particular, on the possible changes of some features of loving relationships.
Methods |
Two hundred outpatients (130 women and 70 men, mean age±SD: 43.4±11.1years) were enrolled. They were suffering from mild or moderate depression, according to DSM–5 criteria, treated with one antidepressant for at least six months and involved in a long-term loving relationship. A specifically designed test, the so-called “sex, attachment, love” (SALT) questionnaire was built to assess the possible changes of the loving relationship.
Results |
The results showed differences between the two genders, in particular women taking TCAs reported more sexual side effects than men, whereas men taking SSRIs complained a reduction of the feelings of love and attachment towards the partner.
Conclusions |
Antidepressants seem to have a dimorphic effect on some elements of loving relationships, however these results need to be further explored.
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Vol 41 - N° S
P. S751 - avril 2017 Retour au numéro
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