Outcomes management is a powerful process for defining, monitoring, and continuously improving practice to enhance the health status of patients. Outcomes management provides patients, providers, and payers with objective data that enhances decision-making about medical care. Case management programs can play an integral role in supporting hospitals and provides efforts to define, measure, and manage outcomes. New skills and support systems are required to do this work well, and successful efforts will reflect careful planning and implementation. The key concepts of outcomes management, how these relate to case management and a case study describing one organization’s experience in bringing these efforts together are described.