Genetic Influences on Bone Density and Bone Turnover : The Heritability of Osteoporosis - 10/07/18
Doi : 10.1016/S1047-9651(18)30454-6
Paul J. Kelly, MD, BS, FRACP a, b, d, ⁎, Nigel A. Morrison, PhD a, Philip N. Sambrook, MD, BS, FRACP a, c, d, Tuan V. Nguyen, MSc a, John A. Eisman, PhD, FRACP a, b, d
a From the Bone and Mineral Research Division, Garvan Institute of Medical Research, Sydney, Australia
b Departments of Endocrinology, Sydney, Australia
c Gerontology, Sydney, Australia
d St Vincent’s Hospital and University of New South Wales, Sydney, Australia
*Address reprint requests to: Paul J. Kelly, MD, BS, FRACP, Bone and Mineral Research Division, Garvan Institute of Medical Research, St Vincent’s Hospital, Sydney NSW, 2010 AustraliaBone and Mineral Research DivisionGarvan Institute of Medical ResearchSt Vincent’s HospitalSydneyNSW2010Australia
Résumé |
Twin and family studies provide strong evidence for a genetic affect on bone density and bone turnover, but identifying the sources of this variance is a major challenge. Understanding of this topic can provide insight into the pathogenesis of osteoporosis and allow a more tailored treatment and prevention of this disorder.
Le texte complet de cet article est disponible en PDF.| This work was supported by the Australian National Health and Medical Research council, The Capital Financial Group, and the National Institutes of Health, USA (Grant RO1-AR-41409-01), Ciba Geigy. |
© 1995
Elsevier Inc. Tous droits réservés.
Vol 6 - N° 3
P. 539-550 - août 1995 Retour au numéro
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