Cervical Glandular Neoplasia : Classification and Staging - 17/05/19
Abstract |
Endocervical adenocarcinomas (EAs) account for 25% of all primary cervical carcinomas. Approximately 85% of EAs are driven by high-risk human papillomavirus (HPV) infection, the most common of which is the so-called usual type endocervical adenocarcinomas. Non-HPV-driven subtypes harbor distinct clinicopathologic features and prognosis and have been increasingly recognized in recent years, which has led to efforts to improve classification of EA based on clinically relevant and reproducible criteria. This review discusses a recently proposed classification system, the International Endocervical Adenocarcinoma Criteria and Classification, which uniquely integrates morphology, cause/pathogenesis, and biological behavior of HPV and non-HPV-driven subtypes of EA.
Le texte complet de cet article est disponible en PDF.Keywords : Cervical adenocarcinoma, Human papillomavirus, Classification, Staging
Plan
| Disclosure Statement: The authors have nothing to disclose. This research was funded in part through the NIH/NCI Cancer Center Support Grant P30 CA008748. |
Vol 12 - N° 2
P. 281-313 - juin 2019 Retour au numéro
Article précédent
- Human Papilloma Virus–Associated Squamous Neoplasia of the Lower Anogenital Tract
- Eric J. Yang
- Benign and Premalignant Lesions of the Endometrium
- Wesley Daniel Mallinger, Charles Matthew Quick
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