Comprehensive analysis of meningioma in the first two decades of life: a systematic review - 03/12/19
Analyse complète des patients atteints de méningiomes au cours des deux premières décennies de la vie: revue systématique
, Antônio Nogueira de Almeida, MD PhD 1, 2, Paulo Henrique Pires de Aguiar, MD PhD 1, Wellingson Silva Paiva, MD PhD 1, Manoel Jacobsen Teixeira, MD PhD 1, Suely Kazue Nagahashi Marie, MD PhD 1Cet article a été publié dans un numéro de la revue, cliquez ici pour y accéder
Abstract |
Purpose: To evaluate the relationship between meningioma histological subtype and tumor site in under-20 year-olds.
Methods: A review of the literature on meningioma during the first 2 decades of life was carried out through a Medline search up to February 2019. To evaluate the adult population, a cross-sectional study was conducted on patients operated on between 2000 and 2014 in a single institution. Exclusion criteria comprised: series reports and papers that lacked detailed description of clinical findings, neuroimaging confirmation of tumor location, and/or at least 5 years’ follow-up.
Results: 107 manuscripts were included, for 365 under-20 year-old patients: 200 male, and 164 female. Histopathology found 197 cases (53.9%) of WHO grade I meningioma, with predominance of meningothelial (41.1%) and transitional (30.9%) subtypes; 123 (33.7%) grade II, and 45 (12.3%) grade III. For 65 (18.25%) of the 356 cases, recurrence was documented, with only 24 deaths (6.7%).
Conclusion: Meningioma in this population presented 2 differences compared to the adult population: male predominance, and high incidence of atypical meningioma. Surgery was the primary treatment. Adjuvant radiotherapy is controversial in the literature.
Le texte complet de cet article est disponible en PDF.Keywords : juvenile population, histopathology, meningioma subtype
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