Autism spectrum disorder (ASD) is characterized by deficits in social communication and interaction and the presence of restricted and repetitive patterns of behavior and interests. Currently, ASD affects 1 in 59 individuals and can be a costly disorder across one’s lifetime. Because of the prevalence, costs, and range of behavioral needs, early intervention is vital to teach skills across a variety of domains and prevent the development or exacerbation of behavioral deficits and excesses. Interventions based on applied behavior analysis have the most empirical support; several strategies to teach social skills, communication, and adaptive skills are discussed.