Response To Tissue Injury - 22/07/20
Doi : 10.1016/S0094-1298(20)32755-3
Ziv M. Peled, MD *, Gyu S. Chin, MD *, Wei Liu, MD PhD *, Robert Galliano, MD *, Michael T. Longaker, MD *
* From the Laboratory of Developmental Biology and Repair (ZMP, GSC, WL), New York University Medical Center (RG, MTL), New York, New York; and University of Connecticut School of Medicine, Farmington, Connecticut (ZMP)
Résumé |
Cutaneous injury, whether by laser, chemical, or scalpel, results in scar formation. The normal response to such an insult occurs in the middle of a continuum of wound repair processes. On one end of the continuum are the overhealed responses (i.e., keloids). On the opposite end are tissue regeneration and scarless healing as seen in fetal wounds. This article reviews the molecular biology and mechanisms leading to these various clinical phenotypes and discusses future potential modalities that may replicate the scarless wound healing mechanism in adults.
Le texte complet de cet article est disponible en PDF.© 2000
Elsevier B.V. Tous droits réservés.
Vol 27 - N° 4
P. 489-500 - octobre 2000 Retour au numéro
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