3D/4D Reconstruction and Quantitative Total Body Imaging - 18/11/20

Doi : 10.1016/j.cpet.2020.09.008

Jinyi Qi, PhD ^a,^⁎,^{^{1
Equal contributions.}} , Samuel Matej, PhD ^b,^{^{1
Equal contributions.}}, Guobao Wang, PhD ^c,^{^{1
Equal contributions.}}, Xuezhu Zhang, PhD ^a
^a Department of Biomedical Engineering, University of California, One Shields Avenue, Davis, CA 95616, USA
^b Department of Radiology, University of Pennsylvania, 3620 Hamilton Walk, John Morgan Building, Room 156A, Philadelphia, PA 19104-6061, USA
^c Department of Radiology, University of California Davis Medical Center, Lawrence J. Ellison Ambulatory Care Center Building, Suite 3100, 4860 Y Street, Sacramento, CA 95817, USA

^∗Corresponding author.

Résumé

Total-body PET image reconstruction follows a similar procedure to the image reconstruction process for standard whole-body PET scanners. One unique aspect of total-body imaging is simultaneous coverage of the entire human body, which makes it convenient to perform total-body dynamic PET scans. Therefore, four-dimensional dynamic PET reconstruction and parametric imaging are of great interest in total-body imaging. This article covers some basics of PET image reconstruction and then focuses on three- and four-dimensional PET reconstruction for total-body imaging. Methods for image formation from raw measurements in total-body PET are described. Challenges and opportunities in total-body PET image reconstruction are discussed.

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Keywords : PET reconstruction, Direct parametric reconstruction, Time of flight, Long axial FOV, Kernel reconstruction, Data corrections