CRISPR technology: The engine that drives cancer therapy - 19/12/20
pages | 14 |
Iconographies | 3 |
Vidéos | 0 |
Autres | 0 |
Highlights |
• | Compared with the previous two generations of gene-editing technology, CRISPR has its unique characteristics. |
• | Four Cas systems are commonly used for CRISPR molecular diagnostics: Cas9, Cas12, Cas13 and Cas14. |
• | CRISPR/Cas gene-editing technology is developing rapidly and has been widely applied in biomedicine. |
• | The application of CRISPR in tumors mainly focuses on the screening of targeted drugs and the cancerous genes. |
• | CRISPR/Cas technology is currently facing a series of difficulties, and need to be overcome. |
Abstract |
CRISPR gene editing technology belongs to the third generation of gene editing technology. Since its discovery, it has attracted the attention of a large number of researchers. Investigators have published a series of academic articles and obtained breakthrough research results through in-depth research. In recent years, this technology has developed rapidly and been widely applied in many fields, especially in medicine. This review focuses on concepts of CRISPR gene editing technology, its application in cancer treatments, its existing limitations, and the new progress in recent years for detailed analysis and sharing.
Le texte complet de cet article est disponible en PDF.Keywords : Cancer, CAR-T, CRISPR, Gene editing, Nanoparticle transport system, Off-target effects
Plan
Vol 133
Article 111007- janvier 2021 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
L’accès au texte intégral de cet article nécessite un abonnement.
Bienvenue sur EM-consulte, la référence des professionnels de santé.
L’achat d’article à l’unité est indisponible à l’heure actuelle.
Déjà abonné à cette revue ?