What factors predict craniomandibular disorders in severe COVID-19 survivors after prolonged intubation? - 27/10/22
, Chatpong Tangmanee b, 1, Wantanee Mutirangura c, 1, Benjamas Apipan d, 1, Prim Auychai e, 1, Jean-Paul Meningaud f, 1, Andreas Neff a, g, 1
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Highlights |
• | If there is/are at least one of these 3 predictors: bilateral molar loss, convex face, and peak C-reactive protein during intensive medical care ≥ 40 mg/l, severe COVID-19 survivors with prolonged intubation (PI) ≥ 1 week should apt to craniomandibular disorder (CMD) screening and/or patient referral to a CMD specialist, regardless of patient's age, gender, underlying CMDs, or previous dental checkups |
• | Aproximately one in every 10 severe COVID-19 survivors (or one in every two to four patient with at least one predictor) will suffer from CMDs within the first six months after PI ≥ 1 week. |
Abstract |
Purposes |
To estimate and identify predictors of craniomandibular disorders (CMDs) in severe COVID-19 survivors after prolonged intubation ≥ 1 week (SCOVIDS-PI).
Methods |
This retrospective study enrolled two cohorts of SCOVIDS-PIs with vs. without CMD during a one-year period. The predictor variables were demographic, dental, anesthetic, and laboratory parameters. The main outcome was presence of CMD until six post-PI months (yes/no). Appropriate statistics were computed with α = 95%.
Results |
The sample comprised 176 subjects aged 59.2 ± 17.2 years (range, 27–89; 11.9% with CMDs; 30.1% females). CMDs were significantly associated with (1) bilateral posterior tooth loss (P = 0; number needed to screen [NNS] = 1.6), (2) dentofacial skeletal class II/convex face (P = .01; NNS = 2.2), and (3) peak CRP during intensive care ≥ 40 mg/l (P = .01; NNS = 3.5). With combined predictors, NNS became 2 to 4.3.
Conclusions |
Three predictors of CMDs in SCOVIDS-PIs: bilateral molar loss, convex face, and CRP ≥ 40 mg/l, indicate CMD screening and/or referral to a CMD specialist, regardless of patients’ age, gender, underlying CMDs, or previous dental checkups. Screening ∼2 to 4 “SCOVIDS-PIs with ≥ one predictor” will identify one CMD events/patients during the first six post-PI months.
Le texte complet de cet article est disponible en PDF.Keywords : Craniomandibular disorder, COVID-19, SARS-CoV-2, Prolonged intubation
Abbreviations : ACE2, CI, CMD, CRP, COVID-19, DGFDT, ICU, MVPs, NNS, OCEBM, ORadj., OTI, PI, RANK, RANKL, RR, rs, SARS-CoV-2, SCOVIDS-PI, STROBE, TMJ, Trp-Kyn
Plan
Vol 123 - N° 6
P. e631-e638 - novembre 2022 Retour au numéro
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