Heart failure with preserved ejection fraction: Association between left atrium strain and NT-ProBNP - 31/12/22
, R. Fekih, M. Abdelhedi, Y. Khelil, A. Boufares, B. Ben Kaab, I. Boussabeh, L. ZakhamaRésumé |
Introduction |
Plasma concentration of NT-ProBNP is recommend as initial diagnostic test in patients with symptoms suggestive of Heart failure (HF) with preserved ejection fraction (HFpEF). The Peak atrial longitudinal strain (PALS) has been proposed as an alternative approach for left ventricular diastolic function assessment.
Objective |
We searched for a correlation between the PALS and the NT-ProBNP in patients with suspected HFpEF.
Method |
This is a prospective descriptive study that included 67 patients with suggestive symptoms of HF, explored in the cardiology department of the hospital of the internal security forces of Marsa and having consulted between November 2021 and March 2022.
Results |
The mean age was 60±11 years, with a sex ratio of 0.76. Hypertension and obesity were the most common cardiovascular risk factors (80% and 51% respectively). Explorations objected a median NT-ProBNP of 76mmHg [49–143] and a median PALS of 30.2 [23–32.4]. A value of NT Pro-BNP≥125pg/mL was found in 33% of the patients. In univariate analysis, PALS was significatively lower in patients with NT Pro-BNP≥125pg/mL (P=0.02). In bivariate analysis, PALS was significatively and negatively correlated with NT-Pro BNP (P=0.003, r=−0.36. The analysis of the Receiver operating characteristic curve showed that a value of PALS<30.2 (sensibility=63%, specificity=77%) increases the likelihood of NT-Pro BNPI≥125pg/mL by 5.6 (OR=5.6, 95% CI: 1.72–18.1).
Conclusion |
PALS, easily measured by echocardiography, could be used as an alternative parameter in the diagnostic of HFpEF.
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Vol 15 - N° 1
P. 102 - janvier 2023 Retour au numéro
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