Antibiotic use in tertiary care hospitals in Bangladesh: Revealing the extent through a point prevalence survey - 15/08/24
, Supta Sarker, MSc, MPH b, A.B.M. Alauddin Chowdhury, MSS, PhD a, Syed Abul Hassan Md. Abdullah, MBBS, MPH c, Md. Shahjahan, MSS, PhD a, Sabrina Sharmin, MSS d, Md. Golam Dostogir Harun, MSS, MPH aRésumé |
Background |
Prevalent use of antibiotics in hospitals results in antimicrobial resistance (AMR), rising mortality, and substantial financial burden. This study assessed the current pattern of antibiotic use among inpatients in tertiary hospitals in Bangladesh.
Methods |
Between August and November 2022, we conducted a point prevalence survey in 4 tertiary hospitals in Dhaka, Bangladesh. The World Health Organization-directed point prevalence survey methodology and tools were followed for the data collection. Descriptive and multivariate statistics were performed using Stata version 15.
Results |
Of 1,063 hospitalized patients, antibiotics were prescribed to 73.5% (781/1063, 95% confidence interval: 70.8-76.1) of patients. A total of 1,164 antibiotics were prescribed, and 49.1% of patients consumed multiple antibiotics. Only 31.4% of patients were prescribed antibiotics based on microbiology results. The reasons for antibiotic prescribing were mentioned only in 19.3% of patients. Infants (adjusted odds ratio: 8.52, P-value: <.001) and neonates (adjusted odds ratio: 4.32, P-value: <.001) were more likely to consume antibiotics compared to adults. Cephalosporins accounted for the majority (54.0%) of antibiotics used in hospitals. None of the hospitals had any antibiotic use guidelines.
Conclusions |
Consumption of Watch group antibiotics empirically among all age groups demonstrates irrational antibiotic usage in Bangladeshi hospitals. Implementation of a tailored stewardship program, antibiotic use guidelines, and prescriber-patient awareness could improve the rational use of antibiotics.
Le texte complet de cet article est disponible en PDF.Highlights |
• | Nearly three-quarters (73.5%) of hospitalized patients were prescribed antibiotics. |
• | Infants and neonates were prescribed a higher number of antibiotics compared to adults. |
• | Antibiotic usage guidelines were not available at any of the hospitals. |
• | 3rd-generation antibiotics (cephalosporins) dominated hospital prescription practice. |
Key Words : Antibiotic, PPS, Hospital, Bangladesh
Plan
| Ethics approval and consent to participate: This study was reviewed and approved by Daffodil International University's Institutional Review Board. Additionally, we requested permission from the respective health care facilities before conducting the study. Prior to the interview, study participants provided written informed consent, including thorough information about the survey's objective, reasons for selection, methodology, risks, advantages, privacy, anonymity, confidentiality, future use of information, right to participate or withdraw, and remuneration policy for participating in this study. |
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| Conflicts of interest: None to report. |
Vol 52 - N° 9
P. 1052-1059 - septembre 2024 Retour au numéro
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