Mycoplasma encephalitis, incomplete Kawasaki disease and MERS, a new association? Short communication - 10/01/26
, Emeline Destombe a, Cécile Grenenko C a, Alice Masurel a, Loic Hery a, Nicolas Deleval c, Antoine Delval c, Elise Daire d, Patrick Berquin a, e, Anne-Gaëlle Le Moing a, bAbstract |
Background |
Mild encephalitis/encephalopathy with a reversible splenial lesion (MERS) is an uncommon clinico-radiological entity, mostly described in children in association with viral or atypical bacterial infections. Mycoplasma pneumoniae (MP) is a rare but recognized trigger. Kawasaki disease (KD) may also present with neurological involvement.
Observation and discussion |
We report the case of a 14-year-old boy with acute encephalopathy, Mycoplasma pneumoniae infection, and features of incomplete KD. Brain MRI showed a reversible lesion in the splenium of the corpus callosum consistent with MERS. The patient developed mucocutaneous signs and transient coronary artery dilatation. He improved with antibiotic and anti-inflammatory therapy.
Conclusion |
This case highlights a rare overlap between MERS, Mycoplasma pneumoniae, and incomplete KD, suggesting shared inflammatory pathways. Clinicians should consider this association when encountering pediatric encephalopathy with systemic inflammatory features.
Le texte complet de cet article est disponible en PDF.Keywords : MERS, Mycoplasma pneumoniae, Kawasaki disease, Splenial lesion, Neuroinflammation
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