Necrotic locally advanced nasal NK/T-cell lymphoma: the timely diagnostic challenge - 26/02/26
Abstract |
Extranodal NK/T-cell lymphoma (ENKTCL) is an aggressive and heterogeneous disease.
It is a rare non-Hodgkin lymphoma observed primarily in Asian and south-American. countries. Most patients with ENKTCL present with early-stage disease.
Herein we present a case of a male patient presented with chronic nasal symptoms, including bad smelling discharges. A midline necrotic lesion was detected on rhinoscopy with destruction of the nasal septum, and necrosis of the philtrum.
The histopathological and flocytometry findings confirmed the diagnosis of Extranodal NK/T-cell lymphoma, nasal type, EBV positive, with Ki 67 at 95%.
ENKTCL presents a diagnostic challenge due to its non-specific and often misleading symptomatology. Better awareness methods about ENKTCL early detection and combined modality therapy may enhance the treatment outcomes in this population of patients.
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Vol 74 - N° 1
Article 103571- janvier 2026 Retour au numéro
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- Corrigendum to “AI-assisted statistical review of 100 oncology research articles: compliance with SAMPL guidelines” [Current Research in Translational Medicine 73 (2025) 103544]
- Michal Ordak
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