^a Department of Cell and Molecular Pharmacology & Experimental Therapeutics, Medical University of South Carolina, Charleston, SC 29425, USA 

^b Department of Psychiatry, Stellenbosch University, Cape Town, South Africa 

^c South African Medical Research Council / Stellenbosch University Genomics of Brain Disorders Research Unit, Department of Psychiatry, Stellenbosch University, Cape Town, South Africa 

^d Department of Neuroscience, Medical University of South Carolina, Charleston, SC 29425, USA 

^e Department of Psychiatry & Behavioral Sciences, Medical University of South Carolina, Charleston, SC 29425, USA 

^f Department of Behavioral Neuroscience, Oregon Health and Science University, Portland, OR 97239, USA 

^g Department of Drug Discovery and Biomedical Sciences, Medical University of South Carolina, Charleston, SC 29425, USA