The longitudinal impact of childhood vision impairment on health, education, physical activity, and social outcomes: A systematic review - 04/04/26

Doi : 10.1016/j.jeph.2026.203371

Masoud Rahmati ^a,^b,^c,^⁎ , Lee Smith ^d,^e, Mapa Prabhath Piyasena ^f, Sooji Lee ^g,^h, Yi Deun Jeong ^g,^h, Laurent Boyer ^a,^d, Cao Duy Nguyen ⁱ, Huyen Do ^j,^k, Bach Xuan Tran ^l,^m, Guillaume Fond ^a, Dong Keon Yon ^g,^h,ⁿ, Hayeon Lee ^h, Bastien Boussat ^o, Tarnjit Sehmbi ^f, Shahina Pardhan ^f,^p

^a AP-HM, CEReSS Research Centre on Health Services and Quality of Life, Aix Marseille University, Marseille, France

^b Department of Physical Education and Sport Sciences, Faculty of Literature and Humanities, Lorestan University, Khorramabad, Iran

^c CRSMP, Center for Mental Health and Psychiatry Research – PACA, Marseille, France

^d Centre for Health, Performance, and Wellbeing, Anglia Ruskin University, Cambridge, UK

^e Department of Public Health, Faculty of Medicine, Biruni University, Istanbul, Turkey

^f Vision and Eye Research Institute, School of Medicine, Anglia Ruskin University, Young Street, Cambridge, United Kingdom

^g Department of Medicine, Kyung Hee University College of Medicine, Seoul, South Korea

^h Center for Digital Health, Medical Science Research Institute, Kyung Hee University Medical Center, Kyung Hee University College of Medicine, Seoul, Republic of Korea

ⁱ Institute for Global Health Innovations, Duy Tan University, Da Nang, Vietnam

^j Research Institute for Advanced Nursing (RIAN), Dong Nai Technology University, Bien Hoa, Vietnam

^k Department of Health Policy and Management, College of Health Science, Korea University, Republic of Korea

^l Faculty of Public Health, VNU University of Medicine and Pharmacy, Vietnam National University, Hanoi, Vietnam

^m International Institute for Training and Research (INSTAR), VNU University of Medicine and Pharmacy, Vietnam National University, Hanoi, Vietnam

ⁿ Department of Pediatrics, Kyung Hee University College of Medicine, Seoul, Republic of Korea

^o TIMC‐IMAG, UMR 5525 JointResearch Unit, Centre National de Recherche Scientifique, National Center for Scientific Research, Université Grenoble‐Alpes, Grenoble, France

^p Centre for Inclusive Community Eye Health, School of Medicine, Anglia Ruskin University, Cambridge UK

^⁎ Corresponding author at: AP-HM, Research Centre on Health Services and Quality of Life, Aix Marseille University, Marseille, France. AP-HM Research Centre on Health Services and Quality of Life Marseille University Marseille France.

Abstract

Introduction

This systematic review aims to investigate the broader implications of vision impairment in children, aiming to provide a more comprehensive understanding of the impact of loss, informing development of effective strategies to control preventable vision impairment through a life-course approach. Our comprehensive literature search revealed no existing systematic reviews directly addressing this review question.

Methods

We conducted a systematic search of the relevant literature using electronic databases searches including PubMed, MEDLINE (Ovid), CENTRAL, and EMBASE from inception of databases up to 20th March 2024 following PRISMA guidelines. Participants included children with vision impairment. The articles were initially screened for title and abstract, and then for full-text reports by two independent reviewers. Study quality was assessed. The outcomes were mortality, mental health, physical health, education, physical activity, and social outcomes. We synthesized and presented the results narratively to provide a comprehensive and structured interpretation of the findings.

Results

Seven articles (57,768 participants, 3–18 years) met the eligibility criteria and were included in the systematic review. Included studies were published between 2000 to 2024 with a median follow-up of 15 years. Vision impairment was linked to a heightened risk of early mortality, and adverse impacts on both physical health and mental health that included increased symptoms of anxiety or depression, and the development of various conditions including metabolic syndrome in adulthood. Vision impairment also had a negative impact on academic performance, lower physical activity, and compromised social outcomes in adolescence and adulthood. The severity of vision impairment was associated with higher magnitude of these effects, with severe impairment having more pronounced impact.

Conclusion

Given the negative associations of vision impairment with various aspects of children's lives in the long term, it is vital that the negative effects of vision impairment are understood and mitigated against as they impact beyond childhood.

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Keywords : Childhood vision impairment, Health, Education, Physical activity, Social outcomes

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Vol 74 - N° 3

Article 203371- juin 2026 Retour au numéro

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The longitudinal impact of childhood vision impairment on health, education, physical activity, and social outcomes: A systematic review - 04/04/26

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