Employment and work absenteeism in individuals living with a vascular liver disease: a European multicenter study - 04/07/26
, Aurélie Plessier b, c , Clémence Ramier d , Laure Elkrief b, e , Virginia Hernandez-Gea f, g , Pierre-Emmanuel Rautou b, c , Katrien Vanthomme h , Hadewijch Vandenheede a , Agnes Dumas d, ⁎ Highlights |
• | VLD patients show lower employment and higher health-related inactivity. |
• | Inactivity driven by disease severity; gastrointestinal bleeding, prior procedures. |
• | Absenteeism driven by pain and unmet need for illness-related leave. |
• | Work limitations stem from medical, social and structural factors. |
• | Greater workplace flexibility could be a key for sustaining employment. |
Abstract |
Background & aims |
Vascular liver diseases (VLDs) are rare conditions affecting adults of working age, yet there are no real-world data on their impact on employment.
Methods |
A multicenter cross-sectional study was conducted in France and Spain, using clinical records and self-administered questionnaires. Employment outcomes in patients with a VLD and controls were compared using indirect standardisation with age- and sex-adjusted population norms. Multivariable logistic regression assessed factors associated with health-related inactivity (unable to work due to illness/disability) and health-related absenteeism from work.
Results |
Of 1136 eligible patients, 595 (52.4%) responded and the data of 432 participants aged 25–64 were analysed. Health-related inactivity (13.0% of patients) and health-related absenteeism over the last year (48.5%) were higher in patients with a VLD than in the general population (Standardised Ratio (SR) = 2.61, 95%CI:1.95–3.42; SR = 1.57, 95%CI:1.33–1.87 respectively). History of gastrointestinal bleeding (adjusted Odds Ratio (aOR) = 2.64, 95%CI:1.17–5.98) and prior interventional procedures (aOR = 2.49, 95%CI:1.06–5.88) were significantly associated with inactivity. Older patients (versus 25–44 years old) and those with a low/moderate educational level (versus high) were more likely to experience inactivity (aOR = 2.23, 95%CI:1.07–4.65; aOR = 3.11, 95%CI:1.53–6.35 respectively). Absenteeism was associated with moderate/severe pain (aOR = 2.45,95%CI:1.10–5.44) and unmet needs for special illness-related leave (aOR = 2.97,95%CI:1.33–6.63).
Conclusions |
Patients with VLD face disadvantages in employment participation and absenteeism, driven by disease severity and symptom burden. These effects are most pronounced among low-educated individuals, highlighting socioeconomic disparities in work retention. This underscores the need for targeted workplace accommodations, supportive employment policies, and social care support.
Le texte complet de cet article est disponible en PDF.Keywords : Rare disease (MeSH), Unemployment (MeSH), Employment (MeSH), Absenteeism (MeSH), Symptom burden (MeSH), Sick leave (MeSH)
Plan
Vol 50 - N° 7
Article 102876- août 2026 Retour au numéro
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